Burkhard Lehner1, Daniela Witte, Stefan Weiss. 1. Division of Orthopedic Oncology and Septic Surgery, Stiftung Orthopädische Universitätsklinik Heidelberg, Schlierbacher Landstrasse 200a, 69118 Heidelberg, Germany.
Abstract
INTRODUCTION: The aim of this study was the investigation of radiological and clinical long-term results after surgery for chondroblastoma in a single orthopedic oncological center. METHOD: As much as 24 patients were enrolled in the study using an in-house tumor data-base (age, sex, patient history, clinical symptoms, type of surgery, complications, and histological results), radiological findings (localization/size of the lesion, Lodwick-classification, Enneking-stages, and local recurrence), and clinical investigation (Enneking score). Mean follow-up was 8 years. RESULTS: Preferred sites were the knee-joint (distal femur 6, proximal tibia 6), followed by the proximal humerus (8), and the proximal femur. As much as 3 lesions were judged inactive, 13 active, and 8 aggressive. Apart from one case, all lesions were treated by curettage and filling of the defect by bone cement and/or cancellous bone chips. Only one patient suffered local recurrence after primary resection of the tumor (4.2%). About 87.5% of our patients reached a very good or good functional result (Enneking score 28-30). CONCLUSION: Our results further support curettage and defect filling even of active/aggressive chondroblastoma. If performed betimes, the surgical therapeutic concept of accurate intralesional curettage with or without local adjuvant therapy and defect packing with cancellous bone grafts and/or bone cement assures a high chance of joint preservation along with a low rate of recurrence and good functional long-term results.
INTRODUCTION: The aim of this study was the investigation of radiological and clinical long-term results after surgery for chondroblastoma in a single orthopedic oncological center. METHOD: As much as 24 patients were enrolled in the study using an in-house tumor data-base (age, sex, patient history, clinical symptoms, type of surgery, complications, and histological results), radiological findings (localization/size of the lesion, Lodwick-classification, Enneking-stages, and local recurrence), and clinical investigation (Enneking score). Mean follow-up was 8 years. RESULTS: Preferred sites were the knee-joint (distal femur 6, proximal tibia 6), followed by the proximal humerus (8), and the proximal femur. As much as 3 lesions were judged inactive, 13 active, and 8 aggressive. Apart from one case, all lesions were treated by curettage and filling of the defect by bone cement and/or cancellous bone chips. Only one patient suffered local recurrence after primary resection of the tumor (4.2%). About 87.5% of our patients reached a very good or good functional result (Enneking score 28-30). CONCLUSION: Our results further support curettage and defect filling even of active/aggressive chondroblastoma. If performed betimes, the surgical therapeutic concept of accurate intralesional curettage with or without local adjuvant therapy and defect packing with cancellous bone grafts and/or bone cement assures a high chance of joint preservation along with a low rate of recurrence and good functional long-term results.
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