Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Prevention and treatment of Pneumocystis carinii pneumonia.

Literature DB >> 2035974

Prevention and treatment of Pneumocystis carinii pneumonia.

Abstract

Several drugs are now available for the treatment and prevention of Pneumocystis carinii pneumonia. These include trimethoprim-sulfamethoxazole and pentamidine isethionate as first-line drugs and dapsone-trimethoprim, trimetrexate, piritrexim, fansidar, difluoromethylornithine, and clindamycin plus primaquine as drugs in later stages of clinical development. A hydroxynaphthoquinone, called 566C80, offers promise in preclinical studies. The use of corticosteroids in the supportive management of P. carinii pneumonitis is undergoing clinical study.

Entities: Chemical Disease Species

Mesh：

Year: 1991 PMID： 2035974 DOI： 10.1146/annurev.me.42.020191.001443

Source DB: PubMed Journal: Annu Rev Med ISSN： 0066-4219 Impact factor: 13.739

Keyword Cloud
Cited

16 in total

1. In vitro suicide inhibition of self-splicing of a group I intron from Pneumocystis carinii by an N3' --> P5' phosphoramidate hexanucleotide.

Authors: S M Testa; S M Gryaznov; D H Turner
Journal: Proc Natl Acad Sci U S A Date: 1999-03-16 Impact factor: 11.205

Review 2. Update on the diagnosis and treatment of Pneumocystis pneumonia.

Authors: Eva M Carmona; Andrew H Limper
Journal: Ther Adv Respir Dis Date: 2010-08-24 Impact factor: 4.031

3. Resuscitation in HIV.

Authors: M C Lipman; M A Johnson
Journal: Genitourin Med Date: 1992-06

4. Sequence and variability of the 5.8S and 26S rRNA genes of Pneumocystis carinii.

Authors: Y Liu; M Rocourt; S Pan; C Liu; M J Leibowitz
Journal: Nucleic Acids Res Date: 1992-07-25 Impact factor: 16.971

5. The unusual 23S rRNA gene of Coxiella burnetii: two self-splicing group I introns flank a 34-base-pair exon, and one element lacks the canonical omegaG.

Authors: Rahul Raghavan; Scott R Miller; Linda D Hicks; Michael F Minnick
Journal: J Bacteriol Date: 2007-07-20 Impact factor: 3.490

6. Crystallographic analysis reveals a novel second binding site for trimethoprim in active site double mutants of human dihydrofolate reductase.

Authors: Vivian Cody; Jim Pace; Jennifer Piraino; Sherry F Queener
Journal: J Struct Biol Date: 2011-06-13 Impact factor: 2.867

Prevention and treatment of Pneumocystis carinii pneumonia.

1. In vitro suicide inhibition of self-splicing of a group I intron from Pneumocystis carinii by an N3' --> P5' phosphoramidate hexanucleotide.

Review 2. Update on the diagnosis and treatment of Pneumocystis pneumonia.

3. Resuscitation in HIV.

4. Sequence and variability of the 5.8S and 26S rRNA genes of Pneumocystis carinii.

5. The unusual 23S rRNA gene of Coxiella burnetii: two self-splicing group I introns flank a 34-base-pair exon, and one element lacks the canonical omegaG.

6. Crystallographic analysis reveals a novel second binding site for trimethoprim in active site double mutants of human dihydrofolate reductase.

7. Variation and in vitro splicing of group I introns in rRNA genes of Pneumocystis carinii.

8. Use of semiquantitative PCR to assess onset and treatment of Pneumocystis carinii infection in rat model.

9. Characterization of the PNT1 pentamidine resistance gene of Saccharomyces cerevisiae.

10. Structure and inhibition of human diamine oxidase.