BACKGROUND: There is an urgent need for the development of cost-effective preventive strategies to reduce the onset of mental disorders. AIMS: To establish the cost-effectiveness of a stepped care preventive intervention for depression and anxiety disorders in older people at high risk of these conditions, compared with routine primary care. METHOD: An economic evaluation was conducted alongside a pragmatic randomised controlled trial (ISRCTN26474556). Consenting individuals presenting with subthreshold levels of depressive or anxiety symptoms were randomly assigned to a preventive stepped care programme (n = 86) or to routine primary care (n = 84). RESULTS: The intervention was successful in halving the incidence rate of depression and anxiety at euro563 ( pound412) per recipient and euro4367 ( pound3196) per disorder-free year gained, compared with routine primary care. The latter would represent good value for money if the willingness to pay for a disorder-free year is at least euro5000. CONCLUSIONS: The prevention programme generated depression- and anxiety-free survival years in the older population at affordable cost.
RCT Entities:
BACKGROUND: There is an urgent need for the development of cost-effective preventive strategies to reduce the onset of mental disorders. AIMS: To establish the cost-effectiveness of a stepped care preventive intervention for depression and anxiety disorders in older people at high risk of these conditions, compared with routine primary care. METHOD: An economic evaluation was conducted alongside a pragmatic randomised controlled trial (ISRCTN26474556). Consenting individuals presenting with subthreshold levels of depressive or anxiety symptoms were randomly assigned to a preventive stepped care programme (n = 86) or to routine primary care (n = 84). RESULTS: The intervention was successful in halving the incidence rate of depression and anxiety at euro563 ( pound412) per recipient and euro4367 ( pound3196) per disorder-free year gained, compared with routine primary care. The latter would represent good value for money if the willingness to pay for a disorder-free year is at least euro5000. CONCLUSIONS: The prevention programme generated depression- and anxiety-free survival years in the older population at affordable cost.
Authors: Charles F Reynolds; Pim Cuijpers; Vikram Patel; Alex Cohen; Amit Dias; Neerja Chowdhary; Olivia I Okereke; Mary Amanda Dew; Stewart J Anderson; Sati Mazumdar; Frank Lotrich; Steven M Albert Journal: Annu Rev Public Health Date: 2012-04 Impact factor: 21.981
Authors: Jim A Haugh; Krista Herbert; Seo Choi; Joanna Petrides; Meagan W Vermeulen; Juliana D'Onofrio Journal: J Clin Psychol Med Settings Date: 2019-12
Authors: Namkee G Choi; C Nathan Marti; Martha L Bruce; Mark T Hegel; Nancy L Wilson; Mark E Kunik Journal: Depress Anxiety Date: 2014-02-05 Impact factor: 6.505
Authors: Agnes J Smink; Cornelia H M van den Ende; Thea P M Vliet Vlieland; Johannes W J Bijlsma; Bart A Swierstra; Joke H Kortland; Theo B Voorn; Steven Teerenstra; Henk J Schers; Joost Dekker; Sita M A Bierma-Zeinstra Journal: Br J Gen Pract Date: 2014-09 Impact factor: 5.386
Authors: Steven M Albert; Jennifer King; Mary Amanda Dew; Amy Begley; Stewart Anderson; Jordan Karp; Ari Gildengers; Meryl Butters; Charles F Reynolds Journal: Am J Geriatr Psychiatry Date: 2015-11-24 Impact factor: 4.105