| Literature DB >> 20339444 |
A K Smilde, J A Westerhuis, H C J Hoefsloot, S Bijlsma, C M Rubingh, D J Vis, R H Jellema, H Pijl, F Roelfsema, J van der Greef.
Abstract
In metabolomics, time-resolved, dynamic or temporal data is more and more collected. The number of methods to analyze such data, however, is very limited and in most cases the dynamic nature of the data is not even taken into account. This paper reviews current methods in use for analyzing dynamic metabolomic data. Moreover, some methods from other fields of science that may be of use to analyze such dynamic metabolomics data are described in some detail. The methods are put in a general framework after providing a formal definition on what constitutes a 'dynamic' method. Some of the methods are illustrated with real-life metabolomics examples.Entities:
Year: 2009 PMID: 20339444 PMCID: PMC2834778 DOI: 10.1007/s11306-009-0191-1
Source DB: PubMed Journal: Metabolomics ISSN: 1573-3882 Impact factor: 4.290