Literature DB >> 20336107

Ageing: Much ado about ageing.

Heidi Ledford.   

Abstract

Mesh：

Substances：

Year:  2010        PMID： 20336107     DOI： 10.1038/464480a

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


× No keyword cloud information.
  11 in total

1.  Specific SIRT1 activation mimics low energy levels and protects against diet-induced metabolic disorders by enhancing fat oxidation.

Authors:  Jérôme N Feige; Marie Lagouge; Carles Canto; Axelle Strehle; Sander M Houten; Jill C Milne; Philip D Lambert; Chikage Mataki; Peter J Elliott; Johan Auwerx
Journal:  Cell Metab       Date:  2008-11       Impact factor: 27.287

2.  Treatment with SRT1720, a SIRT1 activator, ameliorates fatty liver with reduced expression of lipogenic enzymes in MSG mice.

Authors:  Yu Yamazaki; Isao Usui; Yukiko Kanatani; Yuji Matsuya; Koichi Tsuneyama; Shiho Fujisaka; Agussalim Bukhari; Hikari Suzuki; Satoko Senda; Shingo Imanishi; Kazuya Hirata; Manabu Ishiki; Ryuji Hayashi; Masaharu Urakaze; Hideo Nemoto; Masashi Kobayashi; Kazuyuki Tobe
Journal:  Am J Physiol Endocrinol Metab       Date:  2009-09-01       Impact factor: 4.310

3.  Substrate-specific activation of sirtuins by resveratrol.

Authors:  Matt Kaeberlein; Thomas McDonagh; Birgit Heltweg; Jeffrey Hixon; Eric A Westman; Seth D Caldwell; Andrew Napper; Rory Curtis; Peter S DiStefano; Stanley Fields; Antonio Bedalov; Brian K Kennedy
Journal:  J Biol Chem       Date:  2005-01-31       Impact factor: 5.157

4.  The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms.

Authors:  M Kaeberlein; M McVey; L Guarente
Journal:  Genes Dev       Date:  1999-10-01       Impact factor: 11.361

5.  Mechanism of human SIRT1 activation by resveratrol.

Authors:  Margie T Borra; Brian C Smith; John M Denu
Journal:  J Biol Chem       Date:  2005-03-04       Impact factor: 5.157

6.  Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan.

Authors:  Konrad T Howitz; Kevin J Bitterman; Haim Y Cohen; Dudley W Lamming; Siva Lavu; Jason G Wood; Robert E Zipkin; Phuong Chung; Anne Kisielewski; Li-Li Zhang; Brandy Scherer; David A Sinclair
Journal:  Nature       Date:  2003-08-24       Impact factor: 49.962

7.  SRT1720, SRT2183, SRT1460, and resveratrol are not direct activators of SIRT1.

Authors:  Michelle Pacholec; John E Bleasdale; Boris Chrunyk; David Cunningham; Declan Flynn; Robert S Garofalo; David Griffith; Matt Griffor; Pat Loulakis; Brandon Pabst; Xiayang Qiu; Brian Stockman; Venkataraman Thanabal; Alison Varghese; Jessica Ward; Jane Withka; Kay Ahn
Journal:  J Biol Chem       Date:  2010-01-08       Impact factor: 5.157

8.  Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes.

Authors:  Jill C Milne; Philip D Lambert; Simon Schenk; David P Carney; Jesse J Smith; David J Gagne; Lei Jin; Olivier Boss; Robert B Perni; Chi B Vu; Jean E Bemis; Roger Xie; Jeremy S Disch; Pui Yee Ng; Joseph J Nunes; Amy V Lynch; Hongying Yang; Heidi Galonek; Kristine Israelian; Wendy Choy; Andre Iffland; Siva Lavu; Oliver Medvedik; David A Sinclair; Jerrold M Olefsky; Michael R Jirousek; Peter J Elliott; Christoph H Westphal
Journal:  Nature       Date:  2007-11-29       Impact factor: 49.962

9.  Effects of resveratrol on lifespan in Drosophila melanogaster and Caenorhabditis elegans.

Authors:  Timothy M Bass; David Weinkove; Koen Houthoofd; David Gems; Linda Partridge
Journal:  Mech Ageing Dev       Date:  2007-08-14       Impact factor: 5.432

10.  A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange.

Authors:  Yi Liu; Renaud Dentin; Danica Chen; Susan Hedrick; Kim Ravnskjaer; Simon Schenk; Jill Milne; David J Meyers; Phil Cole; John Yates; Jerrold Olefsky; Leonard Guarente; Marc Montminy
Journal:  Nature       Date:  2008-10-05       Impact factor: 49.962
View more
  6 in total

1.  Aging genetics and aging.

Authors:  Sandra Rodríguez-Rodero; Juan Luis Fernández-Morera; Edelmiro Menéndez-Torre; Vincenzo Calvanese; Agustín F Fernández; Mario F Fraga
Journal:  Aging Dis       Date:  2011-04-28       Impact factor: 6.745

2.  Resveratrol and Malignancies.

Authors:  Rodica P Bunaciu; Andrew Yen
Journal:  Curr Pharmacol Rep       Date:  2015-03-10

3.  Compelling comments.

Authors: 
Journal:  Nat Chem Biol       Date:  2011-02       Impact factor: 15.040

Review 4.  Innovation in academic chemical screening: filling the gaps in chemical biology.

Authors:  Samuel A Hasson; James Inglese
Journal:  Curr Opin Chem Biol       Date:  2013-05-14       Impact factor: 8.822

5.  A novel target for Huntington's disease: ERK at the crossroads of signaling. The ERK signaling pathway is implicated in Huntington's disease and its upregulation ameliorates pathology.

Authors:  László Bodai; J Lawrence Marsh
Journal:  Bioessays       Date:  2012-02       Impact factor: 4.345

Review 6.  Interventions to Slow Aging in Humans: Are We Ready?

Authors:  Valter D Longo; Adam Antebi; Andrzej Bartke; Nir Barzilai; Holly M Brown-Borg; Calogero Caruso; Tyler J Curiel; Rafael de Cabo; Claudio Franceschi; David Gems; Donald K Ingram; Thomas E Johnson; Brian K Kennedy; Cynthia Kenyon; Samuel Klein; John J Kopchick; Guenter Lepperdinger; Frank Madeo; Mario G Mirisola; James R Mitchell; Giuseppe Passarino; Karl L Rudolph; John M Sedivy; Gerald S Shadel; David A Sinclair; Stephen R Spindler; Yousin Suh; Jan Vijg; Manlio Vinciguerra; Luigi Fontana
Journal:  Aging Cell       Date:  2015-04-22       Impact factor: 9.304
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.