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Literature DB >> 2031287

Pre-mRNA splicing in yeast.

Abstract

Splicing of introns from nuclear precursor messenger RNAs (pre-mRNAs) occurs in all eukaryotes. Two aspects of the splicing mechanism need to be understood: how intron sequences are recognized and aligned and how splicing is catalysed. Recent genetic and biochemical studies in the simple eukaryote Saccharomyces cerevisiae are revealing some of the features of the splicing mechanism.

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Year: 1991 PMID： 2031287 DOI： 10.1016/0168-9525(91)90276-V

Source DB: PubMed Journal: Trends Genet ISSN： 0168-9525 Impact factor: 11.639

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Cited

119 in total

1. A mutation in a methionine tRNA gene suppresses the prp2-1 Ts mutation and causes a pre-mRNA splicing defect in Saccharomyces cerevisiae.

Authors: D H Kim; G Edwalds-Gilbert; C Ren; R J Lin
Journal: Genetics Date: 1999-11 Impact factor: 4.562

2. Evidence for a base-pairing interaction between U6 small nuclear RNA and 5' splice site during the splicing reaction in yeast.

Authors: H Sawa; J Abelson
Journal: Proc Natl Acad Sci U S A Date: 1992-12-01 Impact factor: 11.205

3. Insertion of non-intron sequence into maize introns interferes with splicing.

Authors: K R Luehrsen; V Walbot
Journal: Nucleic Acids Res Date: 1992-10-11 Impact factor: 16.971

4. A putative homolog of U2AF65 in S. cerevisiae.

Authors: E Birney; S Kumar; A R Krainer
Journal: Nucleic Acids Res Date: 1992-09-11 Impact factor: 16.971

5. Reconstitution of functional mammalian U4 small nuclear ribonucleoprotein: Sm protein binding is not essential for splicing in vitro.

Authors: C Wersig; A Bindereif
Journal: Mol Cell Biol Date: 1992-04 Impact factor: 4.272

Pre-mRNA splicing in yeast.

1. A mutation in a methionine tRNA gene suppresses the prp2-1 Ts mutation and causes a pre-mRNA splicing defect in Saccharomyces cerevisiae.

2. Evidence for a base-pairing interaction between U6 small nuclear RNA and 5' splice site during the splicing reaction in yeast.

3. Insertion of non-intron sequence into maize introns interferes with splicing.

4. A putative homolog of U2AF65 in S. cerevisiae.

5. Reconstitution of functional mammalian U4 small nuclear ribonucleoprotein: Sm protein binding is not essential for splicing in vitro.

6. Alternative modes of mRNA processing in a 3' splice site mutant of Neurospora crassa.

7. Characterization and expression of U1snRNA genes from potato.

8. Analysis of SRrp86-regulated alternative splicing: control of c-Jun and IκBβ activity.

9. The architecture of pre-mRNAs affects mechanisms of splice-site pairing.

10. Dbp73D, a Drosophila gene expressed in ovary, encodes a novel D-E-A-D box protein.