Literature DB >> 20309677

Years from menopause-to-surgery is a major factor in the post-operative subjective outcome for pelvic organ prolapse.

Ki Hoon Ahn1, Tak Kim, Jun Young Hur, Sun Haeng Kim, Kyu Wan Lee, Young Tae Kim.   

Abstract

INTRODUCTION AND HYPOTHESIS: The purpose of the current study was to determine the main factors associated with post-operative subjective outcome in post-menopausal patients with pelvic organ prolapse.
METHODS: Ninety-four women were selected among patients who underwent surgery for grade 3 or 4 prolapse. The outcome was evaluated by the Patient Global Impression of Improvement (PGI-I) scale. Multivariate ordinal regression analysis was performed.
RESULTS: The number of patients with improvement (1 or 2 on the PGI-I scale) was 88 (93.7%). Age and years from menopause-to-surgery were negatively (beta = -0.16, P = 0.01) and positively (beta = 0.14, P = 0.01) associated with the PGI-I scale. The aging effect was lost after adjusting for prolapse grade.
CONCLUSION: The greater the number of years from menopause-to-pelvic organ prolapse surgery, the less satisfied were the patients. The association between older patients and greater satisfaction appears to be a confounding effect of prolapse grade.

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Mesh:

Year:  2010        PMID: 20309677     DOI: 10.1007/s00192-010-1133-1

Source DB:  PubMed          Journal:  Int Urogynecol J        ISSN: 0937-3462            Impact factor:   2.894


  27 in total

1.  17beta-estradiol suppresses proliferation of fibroblasts derived from cardinal ligaments in patients with or without pelvic organ prolapse.

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2.  Pelvic relaxation and associated risk factors: the results of logistic regression analysis.

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4.  Vaginal wall descensus and pelvic floor symptoms in older women.

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5.  Validation of two global impression questionnaires for incontinence.

Authors:  Ilker Yalcin; Richard C Bump
Journal:  Am J Obstet Gynecol       Date:  2003-07       Impact factor: 8.661

6.  Connective tissue alterations in women with pelvic organ prolapse and urinary incontinence.

Authors:  Rafi Suzme; Onay Yalcin; Figen Gurdol; Funda Gungor; Ayhan Bilir
Journal:  Acta Obstet Gynecol Scand       Date:  2007       Impact factor: 3.636

7.  Estradiol rates of change in relation to the final menstrual period in a population-based cohort of women.

Authors:  MaryFran R Sowers; Huiyong Zheng; Daniel McConnell; Bin Nan; Siobán D Harlow; John F Randolph
Journal:  J Clin Endocrinol Metab       Date:  2008-07-22       Impact factor: 5.958

8.  Hormones restore biomechanical properties of the vagina and supportive tissues after surgical menopause in young rats.

Authors:  Pamela A Moalli; Kristen M Debes; Leslie A Meyn; Nancy S Howden; Steven D Abramowitch
Journal:  Am J Obstet Gynecol       Date:  2008-04-08       Impact factor: 8.661

9.  Estrogen levels and estrogen receptors in patients with stress urinary incontinence and pelvic organ prolapse.

Authors:  J H Lang; L Zhu; Z J Sun; J Chen
Journal:  Int J Gynaecol Obstet       Date:  2003-01       Impact factor: 3.561

10.  Levels of tibolone and estradiol and their nonsulfated and sulfated metabolites in serum, myometrium, and vagina of postmenopausal women following treatment for 21 days with tibolone, estradiol, or estradiol plus medroxyprogestrone acetate.

Authors:  Herman A M Verheul; Leen J Blok; Curt W Burger; Payman Hanifi-Moghaddam; Helenius J Kloosterboer
Journal:  Reprod Sci       Date:  2007-02       Impact factor: 3.060

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