| Literature DB >> 2026479 |
J H Malfetano1, J A Blessing, H D Homesley, P Hanjani.
Abstract
Twenty-four evaluable patients with advanced, persistent or recurrent squamous cell carcinoma of the cervix were treated with 750 mg/m2 of gallium nitrate (NSC #15200) every three weeks. No patient had prior cytotoxic chemotherapy. Two patients had a partial response (8.3%), ten patients had stable disease (41.7%), and twelve (50%) had increasing disease. The 95% upper confidence bound for response is 24.0%. The major toxicities were nausea, vomiting and anemia. Gallium nitrate has minimal activity in patients with previously untreated squamous cell carcinoma of the cervix.Entities:
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Year: 1991 PMID： 2026479 DOI： 10.1007/bf00194560
Source DB: PubMed Journal: Invest New Drugs ISSN： 0167-6997 Impact factor: 3.850