Literature DB >> 2025223

Homologues of insulinase, a new superfamily of metalloendopeptidases.

N D Rawlings1, A J Barrett.   

Abstract

On the basis of a statistical analysis of an alignment of the amino acid sequences, a new superfamily of metalloendopeptidases is proposed, consisting of human insulinase, Escherichia coli protease III and mitochondrial processing endopeptidases from Saccharomyces and Neurospora. These enzymes do not contain the 'HEXXH' consensus sequence found in all previously recognized zinc metalloendopeptidases.

Entities:  

Mesh：

Substances：

Year:  1991        PMID： 2025223      PMCID： PMC1150065          DOI： 10.1042/bj2750389

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  36 in total

1.  A family of mitochondrial proteins involved in bioenergetICS and biogenesis.

Authors:  U Schulte; M Arretz; H Schneider; M Tropschug; E Wachter; W Neupert; H Weiss
Journal:  Nature       Date:  1989-05-11       Impact factor: 49.962

2.  Two mitochondrial matrix proteases act sequentially in the processing of mammalian matrix enzymes.

Authors:  F Kalousek; J P Hendrick; L E Rosenberg
Journal:  Proc Natl Acad Sci U S A       Date:  1988-10       Impact factor: 11.205

3.  A unique signature identifies a family of zinc-dependent metallopeptidases.

Authors:  C V Jongeneel; J Bouvier; A Bairoch
Journal:  FEBS Lett       Date:  1989-01-02       Impact factor: 4.124

4.  Import of the malate dehydrogenase precursor by mitochondria. Cleavage within leader peptide by matrix protease leads to formation of intermediate-sized form.

Authors:  E S Sztul; T W Chu; A W Strauss; L E Rosenberg
Journal:  J Biol Chem       Date:  1988-08-25       Impact factor: 5.157

5.  Human insulin-degrading enzyme shares structural and functional homologies with E. coli protease III.

Authors:  J A Affholter; V A Fried; R A Roth
Journal:  Science       Date:  1988-12-09       Impact factor: 47.728

6.  Cloning and expression of the cDNA for a Drosophila insulin-degrading enzyme.

Authors:  W L Kuo; B D Gehm; M R Rosner
Journal:  Mol Endocrinol       Date:  1990-10

7.  Isolation and characterization of an insulin-degrading enzyme from Drosophila melanogaster.

Authors:  J V Garcia; B W Fenton; M R Rosner
Journal:  Biochemistry       Date:  1988-06-14       Impact factor: 3.162

8.  Cyclosporin A-binding protein (cyclophilin) of Neurospora crassa. One gene codes for both the cytosolic and mitochondrial forms.

Authors:  M Tropschug; D W Nicholson; F U Hartl; H Köhler; N Pfanner; E Wachter; W Neupert
Journal:  J Biol Chem       Date:  1988-10-05       Impact factor: 5.157

9.  The processing peptidase of yeast mitochondria: the two co-operating components MPP and PEP are structurally related.

Authors:  R A Pollock; F U Hartl; M Y Cheng; J Ostermann; A Horwich; W Neupert
Journal:  EMBO J       Date:  1988-11       Impact factor: 11.598

10.  Import of proteins into yeast mitochondria: the nuclear MAS2 gene encodes a component of the processing protease that is homologous to the MAS1-encoded subunit.

Authors:  R E Jensen; M P Yaffe
Journal:  EMBO J       Date:  1988-12-01       Impact factor: 11.598
View more
  23 in total

1.  An unusual active site identified in a family of zinc metalloendopeptidases.

Authors:  A B Becker; R A Roth
Journal:  Proc Natl Acad Sci U S A       Date:  1992-05-01       Impact factor: 11.205

2.  Characterization of the bacterial metalloendopeptidase pitrilysin by use of a continuous fluorescence assay.

Authors:  A Anastasi; C G Knight; A J Barrett
Journal:  Biochem J       Date:  1993-03-01       Impact factor: 3.857

Review 3.  Mitochondrial protein import in plants. Signals, sorting, targeting, processing and regulation.

Authors:  E Glaser; S Sjöling; M Tanudji; J Whelan
Journal:  Plant Mol Biol       Date:  1998-09       Impact factor: 4.076

Review 4.  The mitochondrial processing peptidase: function and specificity.

Authors:  P Luciano; V Géli
Journal:  Experientia       Date:  1996-12-15

Review 5.  Botulinum Neurotoxins: Biology, Pharmacology, and Toxicology.

Authors:  Marco Pirazzini; Ornella Rossetto; Roberto Eleopra; Cesare Montecucco
Journal:  Pharmacol Rev       Date:  2017-04       Impact factor: 25.468

Review 6.  Architecture and function of metallopeptidase catalytic domains.

Authors:  Núria Cerdà-Costa; Francesc Xavier Gomis-Rüth
Journal:  Protein Sci       Date:  2014-02       Impact factor: 6.725

7.  The beta subunit of the mitochondrial processing peptidase from rat liver: cloning and sequencing of a cDNA and comparison with a proposed family of metallopeptidases.

Authors:  V Paces; L E Rosenberg; W A Fenton; F Kalousek
Journal:  Proc Natl Acad Sci U S A       Date:  1993-06-01       Impact factor: 11.205

8.  The Cytochrome c Reductase Integrated Processing Peptidase from Potato Mitochondria Belongs to a New Class of Metalloendoproteases.

Authors:  M. Emmermann; U. K. Schmitz
Journal:  Plant Physiol       Date:  1993-10       Impact factor: 8.340

9.  Substrate specificity of the metalloproteinase pregnancy-associated plasma protein-A (PAPP-A) assessed by mutagenesis and analysis of synthetic peptides: substrate residues distant from the scissile bond are critical for proteolysis.

Authors:  Lisbeth S Laursen; Michael T Overgaard; Claus G Nielsen; Henning B Boldt; Kathrin H Hopmann; Cheryl A Conover; Lars Sottrup-Jensen; Linda C Giudice; Claus Oxvig
Journal:  Biochem J       Date:  2002-10-01       Impact factor: 3.857

10.  Tn5-directed cloning of pqq genes from Pseudomonas fluorescens CHA0: mutational inactivation of the genes results in overproduction of the antibiotic pyoluteorin.

Authors:  U Schnider; C Keel; C Voisard; G Défago; D Haas
Journal:  Appl Environ Microbiol       Date:  1995-11       Impact factor: 4.792
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.