Literature DB >> 20237737

Inadvertent use of bevacizumab to treat choroidal neovascularisation during pregnancy: a case report.

Ziqiang Wu1, Jingjing Huang, Srinivas Sadda.   

Abstract

INTRODUCTION: This study reports a case of bevacizumab administered to treat choroidal neovascularisation in a woman later discovered to be pregnant. CLINICAL PICTURE: A 25-year-old pregnant woman developed myopic choroidal neovascularisation in both eyes. TREATMENT: Both eyes were treated with a total of 3 intravitreal injections of bevacizumab sequentially. OUTCOME: Vision improved significantly in both eyes. There were no evident pregnancy-related complications at 1 year postpartum.
CONCLUSION: Although anti-vascular endothelial growth factor (VEGF) therapy did not result in any detectable short-term adverse event in this mother and baby, the potential toxicity of these agents must be carefully considered in pregnant patients.

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Year:  2010        PMID: 20237737

Source DB:  PubMed          Journal:  Ann Acad Med Singapore        ISSN: 0304-4602            Impact factor:   2.473


  10 in total

Review 1.  [Ophthalmic agents during pregnancy and breastfeeding].

Authors:  T Ness; W Paulus
Journal:  Ophthalmologe       Date:  2012-03       Impact factor: 1.059

2.  Idiopathic choroidal neovascularisation in pregnancy: treatment options and a successful outcome.

Authors:  Samantha Roshani De Silva; Farhat Bibi; Kuan Sim; Mandeep Singh Bindra
Journal:  BMJ Case Rep       Date:  2016-07-19

3.  Dexamethasone intravitreal implant for diabetic macular edema in a pregnant patient.

Authors:  Romi Yoo; Hyung Chan Kim; Hyewon Chung
Journal:  Int J Ophthalmol       Date:  2016-10-18       Impact factor: 1.779

Review 4.  Ocular changes during pregnancy.

Authors:  Friederike Mackensen; Wolfgang E Paulus; Regina Max; Thomas Ness
Journal:  Dtsch Arztebl Int       Date:  2014-08-18       Impact factor: 5.594

5.  Intravitreal bevacizumab injection in unrecognised early pregnancy.

Authors:  L Sullivan; S P Kelly; A Glenn; C P R Williams; M McKibbin
Journal:  Eye (Lond)       Date:  2014-01-17       Impact factor: 3.775

Review 6.  Intravitreal Anti-VEGF Injections in Pregnancy: Case Series and Review of Literature.

Authors:  Silvio Polizzi; Vinit B Mahajan
Journal:  J Ocul Pharmacol Ther       Date:  2015-08-24       Impact factor: 2.671

Review 7.  Intravitreal anti-vascular endothelial growth factor medications during pregnancy: current perspective.

Authors:  Morteza Naderan; Masomeh Sabzevary; Keivan Rezaii; Ali Banafshehafshan; Seddigheh Hantoushzadeh
Journal:  Int Ophthalmol       Date:  2020-10-12       Impact factor: 2.031

8.  Intravitreal vascular endothelial growth factor (VEGF) inhibitor injection in unrecognised early pregnancy.

Authors:  Farzan Kianersi; Heshmatollah Ghanbari; Zahra Naderi Beni; Afsaneh Naderi Beni
Journal:  Invest New Drugs       Date:  2016-06-02       Impact factor: 3.850

Review 9.  Diabetic retinopathy and diabetic macular oedema pathways and management: UK Consensus Working Group.

Authors:  Winfried M Amoaku; Faruque Ghanchi; Clare Bailey; Sanjiv Banerjee; Somnath Banerjee; Louise Downey; Richard Gale; Robin Hamilton; Kamlesh Khunti; Esther Posner; Fahd Quhill; Stephen Robinson; Roopa Setty; Dawn Sim; Deepali Varma; Hemal Mehta
Journal:  Eye (Lond)       Date:  2020-06       Impact factor: 3.775

10.  Teratogenic Effects of Intravitreal Injection of Bevacizumab in a Pregnant Rat Model.

Authors:  Shahram Bamdad; Mina Bamdad; Mahsa Khanlari; Yahya Daneshbod; Behzad Khademi
Journal:  Iran J Pharm Res       Date:  2017       Impact factor: 1.696

  10 in total

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