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Literature DB >> 20234910

DNA-catalyzed serine side chain reactivity and selectivity.

Abstract

New deoxyribozymes are shown to catalyze reactions of serine side chains, forming nucleopeptide linkages and discriminating between serine and tyrosine or between two competing serines.

Entities: Chemical Species

Mesh：

Substances：

Year: 2010 PMID： 20234910 PMCID： PMC2841799 DOI： 10.1039/b927317d

Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222

23 in total

1. Protein is linked to the 5' end of poliovirus RNA by a phosphodiester linkage to tyrosine.

Authors: V Ambros; D Baltimore
Journal: J Biol Chem Date: 1978-08-10 Impact factor: 5.157

2. O4-(5'-uridylyl)tyrosine is the bond between the genome-linked protein and the RNA of poliovirus.

Authors: P G Rothberg; T J Harris; A Nomoto; E Wimmer
Journal: Proc Natl Acad Sci U S A Date: 1978-10 Impact factor: 11.205

3. Covalent bonds between protein and DNA. Formation of phosphotyrosine linkage between certain DNA topoisomerases and DNA.

Authors: Y C Tse; K Kirkegaard; J C Wang
Journal: J Biol Chem Date: 1980-06-25 Impact factor: 5.157

4. Initiation of phage phi 29 DNA replication in vitro: formation of a covalent complex between the terminal protein, p3, and 5'-dAMP.

Authors: M A Peñalva; M Salas
Journal: Proc Natl Acad Sci U S A Date: 1982-09 Impact factor: 11.205

5. A DNA enzyme that cleaves RNA.

Authors: R R Breaker; G F Joyce
Journal: Chem Biol Date: 1994-12

6. The tumor suppressor p53 is bound to RNA by a stable covalent linkage.

Authors: A Samad; R B Carroll
Journal: Mol Cell Biol Date: 1991-03 Impact factor: 4.272

7. Deoxyribozymes with 2'-5' RNA ligase activity.

Authors: Amber Flynn-Charlebois; Yangming Wang; Tracey K Prior; Imran Rashid; Kelly A Hoadley; Rebecca L Coppins; Amanda C Wolf; Scott K Silverman
Journal: J Am Chem Soc Date: 2003-03-05 Impact factor: 15.419

Review 8. Directed evolution of nucleic acid enzymes.

Authors: Gerald F Joyce
Journal: Annu Rev Biochem Date: 2004 Impact factor: 23.643

9. A human 5'-tyrosyl DNA phosphodiesterase that repairs topoisomerase-mediated DNA damage.

Authors: Felipe Cortes Ledesma; Sherif F El Khamisy; Maria C Zuma; Kay Osborn; Keith W Caldecott
Journal: Nature Date: 2009-10-01 Impact factor: 49.962

10. Protein p3 is linked to the DNA of phage phi 29 through a phosphoester bond between serine and 5'-dAMP.

Authors: J M Hermoso; M Salas
Journal: Proc Natl Acad Sci U S A Date: 1980-11 Impact factor: 11.205

12 in total

1. DNA-catalyzed covalent modification of amino acid side chains in tethered and free peptide substrates.

Authors: On Yi Wong; P I Pradeepkumar; Scott K Silverman
Journal: Biochemistry Date: 2011-05-03 Impact factor: 3.162

2. DNA-catalyzed reactivity of a phosphoramidate functional group and formation of an unusual pyrophosphoramidate linkage.

Authors: Amit Sachdeva; Scott K Silverman
Journal: Org Biomol Chem Date: 2011-11-01 Impact factor: 3.876

DNA-catalyzed serine side chain reactivity and selectivity.

1. Protein is linked to the 5' end of poliovirus RNA by a phosphodiester linkage to tyrosine.

2. O4-(5'-uridylyl)tyrosine is the bond between the genome-linked protein and the RNA of poliovirus.

3. Covalent bonds between protein and DNA. Formation of phosphotyrosine linkage between certain DNA topoisomerases and DNA.

4. Initiation of phage phi 29 DNA replication in vitro: formation of a covalent complex between the terminal protein, p3, and 5'-dAMP.

5. A DNA enzyme that cleaves RNA.

6. The tumor suppressor p53 is bound to RNA by a stable covalent linkage.

7. Deoxyribozymes with 2'-5' RNA ligase activity.

Review 8. Directed evolution of nucleic acid enzymes.

9. A human 5'-tyrosyl DNA phosphodiesterase that repairs topoisomerase-mediated DNA damage.

10. Protein p3 is linked to the DNA of phage phi 29 through a phosphoester bond between serine and 5'-dAMP.

1. DNA-catalyzed covalent modification of amino acid side chains in tethered and free peptide substrates.

2. DNA-catalyzed reactivity of a phosphoramidate functional group and formation of an unusual pyrophosphoramidate linkage.

3. Covalent tagging of phosphorylated peptides by phosphate-specific deoxyribozymes.

4. Pursuing DNA catalysts for protein modification.

5. Catalytic DNA with phosphatase activity.

6. DNA-catalyzed lysine side chain modification.

7. Biochemical and Biophysical Understanding of Metal Ion Selectivity of DNAzymes.

8. A generalizable DNA-catalyzed approach to peptide-nucleic acid conjugation.

9. DNA catalysts with tyrosine kinase activity.

10. Systematic evaluation of the dependence of deoxyribozyme catalysis on random region length.