Literature DB >> 2023432

Investigation of the antispasmodic potential of Hibiscus sabdariffa calyces.

M B Ali1, W M Salih, A H Mohamed, A M Homeida.   

Abstract

Addition of an aqueous extract of Hibiscus sabdariffa calyces (2.5 ml/bath approximately 125 mg of starting crude material) inhibited the tone of various isolated muscle preparations (rabbit aortic strip, rhythmically contracting rat uterus, guinea-pig tracheal chain and rat diaphragm). Other muscles were stimulated (quiescent rat uterus and frog rectus abdominis). Intravenous injection of the extract to anaesthetized cats lowered the blood pressure in a dose-response manner. The inhibitory effects were resistant to a number of standard receptor blockers but the hypotensive influence was partially blocked by atropine and the tonic effects on rat uterus were partially reduced by hydrocortisone and indomethacin.

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Year:  1991        PMID： 2023432     DOI： 10.1016/0378-8741(91)90009-3

Source DB:  PubMed          Journal:  J Ethnopharmacol        ISSN： 0378-8741            Impact factor:   4.360


  7 in total

1.  Phytochemical Analysis, Antioxidant, Antimicrobial, and Anti-Swarming Properties of Hibiscus sabdariffa L. Calyx Extracts: In Vitro and In Silico Modelling Approaches.

Authors:  Bechr Hamrita; Noumi Emira; Adele Papetti; Riadh Badraoui; Lamjed Bouslama; Mohamed-Iheb Ben Tekfa; Assia Hamdi; Mitesh Patel; Abdelbaset Mohamed Elasbali; Mohd Adnan; Syed Amir Ashraf; Mejdi Snoussi
Journal:  Evid Based Complement Alternat Med       Date:  2022-05-20       Impact factor: 2.650

2.  Comparative study of anthocyanin and volatile compounds content of four varieties of Mexican roselle (Hibiscus sabdariffa L.) by multivariable analysis.

Authors:  G A Camelo-Méndez; J A Ragazzo-Sánchez; A R Jiménez-Aparicio; P E Vanegas-Espinoza; O Paredes-López; A A Del Villar-Martínez
Journal:  Plant Foods Hum Nutr       Date:  2013-09       Impact factor: 3.921

3.  The effect of hibiscus sabdariffa on lipid profile, creatinine, and serum electrolytes: a randomized clinical trial.

Authors:  Abbas Mohagheghi; Shirin Maghsoud; Patricia Khashayar; Mohammad Ghazi-Khansari
Journal:  ISRN Gastroenterol       Date:  2010-11-07

Review 4.  Hibiscus sabdariffa L., roselle calyx, from ethnobotany to pharmacology.

Authors:  Octavio Carvajal-Zarrabal; Dulce María Barradas-Dermitz; Zaida Orta-Flores; Patricia Margaret Hayward-Jones; Cirilo Nolasco-Hipólito; M Guadalupe Aguilar-Uscanga; Anilú Miranda-Medina; Kopli Bin Bujang
Journal:  J Exp Pharmacol       Date:  2012-02-28

5.  Effects of aqueous extract of Hibiscus sabdariffa on the renin-angiotensin-aldosterone system of Nigerians with mild to moderate essential hypertension: A comparative study with lisinopril.

Authors:  Daniel Chukwu Nwachukwu; Eddy Ikemefuna Aneke; Leonard Fidelis Obika; Nkiru Zuada Nwachukwu
Journal:  Indian J Pharmacol       Date:  2015 Sep-Oct       Impact factor: 1.200

Review 6.  Ethnomedicinal, Phytochemical and Ethnopharmacological Aspects of Four Medicinal Plants of Malvaceae Used in Indian Traditional Medicines: A Review.

Authors:  Jasmeet Kaur Abat; Sanjay Kumar; Aparajita Mohanty
Journal:  Medicines (Basel)       Date:  2017-10-18

7.  Aqueous Fraction from Hibiscus sabdariffa Relaxes Mesenteric Arteries of Normotensive and Hypertensive Rats through Calcium Current Reduction and Possibly Potassium Channels Modulation.

Authors:  Anas M A Alsayed; Bei Li Zhang; Pierre Bredeloux; Leslie Boudesocque-Delaye; Angèle Yu; Nicolas Peineau; Cécile Enguehard-Gueiffier; Elhadi M Ahmed; Côme Pasqualin; Véronique Maupoil
Journal:  Nutrients       Date:  2020-06-15       Impact factor: 5.717
  7 in total

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