Literature DB >> 20229567

Azides derived from colchicine and their use in library synthesis: A practical entry to new bioactive derivatives of an old natural drug.

Norman Nicolaus1, Janet Zapke, Philipp Riesterer, Jörg-Martin Neudörfl, Aram Prokop, Hartmut Oschkinat, Hans-Günther Schmalz.   

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Year:  2010        PMID： 20229567     DOI： 10.1002/cmdc.201000063

Source DB:  PubMed          Journal:  ChemMedChem        ISSN： 1860-7179            Impact factor:   3.466


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  6 in total

1.  New Colchicine-Derived Triazoles and Their Influence on Cytotoxicity and Microtubule Morphology.

Authors:  Persefoni Thomopoulou; Julia Sachs; Nicole Teusch; Aruljothi Mariappan; Jay Gopalakrishnan; Hans-Günther Schmalz
Journal:  ACS Med Chem Lett       Date:  2015-12-29       Impact factor: 4.345

Review 2.  Application of triazoles as bioisosteres and linkers in the development of microtubule targeting agents.

Authors:  M Shaheer Malik; Saleh A Ahmed; Ismail I Althagafi; Mohammed Azam Ansari; Ahmed Kamal
Journal:  RSC Med Chem       Date:  2020-01-29

3.  B-nor-methylene Colchicinoid PT-100 Selectively Induces Apoptosis in Multidrug-Resistant Human Cancer Cells via an Intrinsic Pathway in a Caspase-Independent Manner.

Authors:  Andreas Stein; Persefoni Hilken Née Thomopoulou; Corazon Frias; Sina M Hopff; Paloma Varela; Nicola Wilke; Arul Mariappan; Jörg-Martin Neudörfl; Alexey Yu Fedorov; Jay Gopalakrishnan; Benoît Gigant; Aram Prokop; Hans-Günther Schmalz
Journal:  ACS Omega       Date:  2022-01-11

4.  Structure-Activity Relationship Studies of β-Lactam-azide Analogues as Orally Active Antitumor Agents Targeting the Tubulin Colchicine Site.

Authors:  Dong-Jun Fu; Ling Fu; Ying-Chao Liu; Jun-Wei Wang; Yu-Qing Wang; Bing-Kai Han; Xiao-Rui Li; Chuang Zhang; Feng Li; Jian Song; Bing Zhao; Ruo-Wang Mao; Ruo-Han Zhao; Sai-Yang Zhang; Li Zhang; Yan-Bing Zhang; Hong-Min Liu
Journal:  Sci Rep       Date:  2017-10-06       Impact factor: 4.379

5.  Metal-Dependent Cytotoxic and Kinesin Spindle Protein Inhibitory Activity of Ru, Os, Rh, and Ir Half-Sandwich Complexes of Ispinesib-Derived Ligands.

Authors:  Michał Łomzik; Muhammad Hanif; Aleksandra Budniok; Andrzej Błauż; Anna Makal; Daniel M Tchoń; Barbara Leśniewska; Kelvin K H Tong; Sanam Movassaghi; Tilo Söhnel; Stephen M F Jamieson; Ayesha Zafar; Jóhannes Reynisson; Błażej Rychlik; Christian G Hartinger; Damian Plażuk
Journal:  Inorg Chem       Date:  2020-10-01       Impact factor: 5.165

6.  Regioselective approach to colchiceine tropolone ring functionalization at C(9) and C(10) yielding new anticancer hybrid derivatives containing heterocyclic structural motifs.

Authors:  Krystian Pyta; Natalia Skrzypczak; Piotr Ruszkowski; Franz Bartl; Piotr Przybylski
Journal:  J Enzyme Inhib Med Chem       Date:  2022-12       Impact factor: 5.051
  6 in total

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