Literature DB >> 20229094

Is type 2 diabetes an amyloidosis and does it really matter (to patients)?

G J S Cooper1, J F Aitken, S Zhang.   

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Year:  2010        PMID: 20229094     DOI: 10.1007/s00125-010-1715-y

Source DB:  PubMed          Journal:  Diabetologia        ISSN: 0012-186X            Impact factor:   10.122


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  53 in total

1.  Ultrastructural evidence that apoptosis is the mechanism by which human amylin evokes death in RINm5F pancreatic islet beta-cells.

Authors:  E L Saafi; B Konarkowska; S Zhang; J Kistler; G J Cooper
Journal:  Cell Biol Int       Date:  2001       Impact factor: 3.612

2.  Spontaneous diabetes mellitus in transgenic mice expressing human islet amyloid polypeptide.

Authors:  J Janson; W C Soeller; P C Roche; R T Nelson; A J Torchia; D K Kreutter; P C Butler
Journal:  Proc Natl Acad Sci U S A       Date:  1996-07-09       Impact factor: 11.205

3.  Watching amyloid fibrils grow by time-lapse atomic force microscopy.

Authors:  C Goldsbury; J Kistler; U Aebi; T Arvinte; G J Cooper
Journal:  J Mol Biol       Date:  1999-01-08       Impact factor: 5.469

4.  Islet amyloid polypeptide: pinpointing amino acid residues linked to amyloid fibril formation.

Authors:  P Westermark; U Engström; K H Johnson; G T Westermark; C Betsholtz
Journal:  Proc Natl Acad Sci U S A       Date:  1990-07       Impact factor: 11.205

5.  Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients.

Authors:  G J Cooper; A C Willis; A Clark; R C Turner; R B Sim; K B Reid
Journal:  Proc Natl Acad Sci U S A       Date:  1987-12       Impact factor: 11.205

6.  Induction of apoptosis by human amylin in RINm5F islet beta-cells is associated with enhanced expression of p53 and p21WAF1/CIP1.

Authors:  S Zhang; J Liu; E L Saafi; G J Cooper
Journal:  FEBS Lett       Date:  1999-07-23       Impact factor: 4.124

Review 7.  The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics.

Authors:  John Hardy; Dennis J Selkoe
Journal:  Science       Date:  2002-07-19       Impact factor: 47.728

Review 8.  Amylin and the amylin gene: structure, function and relationship to islet amyloid and to diabetes mellitus.

Authors:  G J Cooper; A J Day; A C Willis; A N Roberts; K B Reid; B Leighton
Journal:  Biochim Biophys Acta       Date:  1989-12-14

9.  Molecular and functional characterization of amylin, a peptide associated with type 2 diabetes mellitus.

Authors:  A N Roberts; B Leighton; J A Todd; D Cockburn; P N Schofield; R Sutton; S Holt; Y Boyd; A J Day; E A Foot
Journal:  Proc Natl Acad Sci U S A       Date:  1989-12       Impact factor: 11.205

10.  Spontaneous diabetes in hemizygous human amylin transgenic mice that developed neither islet amyloid nor peripheral insulin resistance.

Authors:  Winifred P S Wong; David W Scott; Chia-Lin Chuang; Shaoping Zhang; Hong Liu; Athena Ferreira; Etuate L Saafi; Yee Soon Choong; Garth J S Cooper
Journal:  Diabetes       Date:  2008-07-15       Impact factor: 9.461

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  13 in total

Review 1.  The receptor for advanced glycation endproducts is a mediator of toxicity by IAPP and other proteotoxic aggregates: Establishing and exploiting common ground for novel amyloidosis therapies.

Authors:  Andisheh Abedini; Julia Derk; Ann Marie Schmidt
Journal:  Protein Sci       Date:  2018-07       Impact factor: 6.725

2.  Islet Amyloid Polypeptide Membrane Interactions: Effects of Membrane Composition.

Authors:  Xiaoxue Zhang; Johnna R St Clair; Erwin London; Daniel P Raleigh
Journal:  Biochemistry       Date:  2017-01-05       Impact factor: 3.162

Review 3.  Therapeutic potential of copper chelation with triethylenetetramine in managing diabetes mellitus and Alzheimer's disease.

Authors:  Garth J S Cooper
Journal:  Drugs       Date:  2011-07-09       Impact factor: 9.546

Review 4.  Islet amyloid: from fundamental biophysics to mechanisms of cytotoxicity.

Authors:  Ping Cao; Peter Marek; Harris Noor; Vadim Patsalo; Ling-Hsien Tu; Hui Wang; Andisheh Abedini; Daniel P Raleigh
Journal:  FEBS Lett       Date:  2013-02-01       Impact factor: 4.124

Review 5.  Mechanisms of islet amyloidosis toxicity in type 2 diabetes.

Authors:  Andisheh Abedini; Ann Marie Schmidt
Journal:  FEBS Lett       Date:  2013-01-18       Impact factor: 4.124

Review 6.  Aggregation of islet amyloid polypeptide: from physical chemistry to cell biology.

Authors:  Ping Cao; Andisheh Abedini; Daniel P Raleigh
Journal:  Curr Opin Struct Biol       Date:  2012-12-22       Impact factor: 6.809

7.  Time-resolved studies define the nature of toxic IAPP intermediates, providing insight for anti-amyloidosis therapeutics.

Authors:  Andisheh Abedini; Annette Plesner; Ping Cao; Zachary Ridgway; Jinghua Zhang; Ling-Hsien Tu; Chris T Middleton; Brian Chao; Daniel J Sartori; Fanling Meng; Hui Wang; Amy G Wong; Martin T Zanni; C Bruce Verchere; Daniel P Raleigh; Ann Marie Schmidt
Journal:  Elife       Date:  2016-05-23       Impact factor: 8.140

8.  Structural similarities and differences between amyloidogenic and non-amyloidogenic islet amyloid polypeptide (IAPP) sequences and implications for the dual physiological and pathological activities of these peptides.

Authors:  Chun Wu; Joan-Emma Shea
Journal:  PLoS Comput Biol       Date:  2013-08-29       Impact factor: 4.475

9.  Defining the molecular basis of amyloid inhibitors: human islet amyloid polypeptide-insulin interactions.

Authors:  Anna C Susa; Chun Wu; Summer L Bernstein; Nicholas F Dupuis; Hui Wang; Daniel P Raleigh; Joan-Emma Shea; Michael T Bowers
Journal:  J Am Chem Soc       Date:  2014-09-04       Impact factor: 15.419

Review 10.  Islet Amyloid Polypeptide: Structure, Function, and Pathophysiology.

Authors:  Rehana Akter; Ping Cao; Harris Noor; Zachary Ridgway; Ling-Hsien Tu; Hui Wang; Amy G Wong; Xiaoxue Zhang; Andisheh Abedini; Ann Marie Schmidt; Daniel P Raleigh
Journal:  J Diabetes Res       Date:  2015-11-15       Impact factor: 4.011

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