PURPOSE: To evaluate the value of T2w endorectal MRI (eMRI) for correct detection of tumor foci within the prostate regarding tumor size. MATERIALS AND METHODS: 70 patients with histologically proven prostate cancer were examined with T2w eMRI before radical prostatectomy at a 1.5T scanner. For evaluation of eMRI, two radiologists evaluated each tumor focus within the gland. After radical prostatectomy, the prostates were prepared as whole-mount sections, according to transversal T2w eMRI. For each slice, tumor surroundings were marked and compared with eMRI. Based on whole-mount section, 315 slices were evaluated and 533 tumor lesions were documented. RESULTS: Based on the T2w eMRI, 213 tumor lesions were described. In 137/213, histology could prove these lesions. EMRI was able to visualize 0/56 lesions with a maximum size of <0.3 cm (detection rate 0%), between 0.3 and 0.5 cm 4/116 (3%), between 1 and 0.5 cm 22/169 (13%), between 2 and 1cm 61/136 (45%) and for >2 cm 50/56 (89%). False positive eMRI findings were: <0.3 cm n=0, 0.5-0.3 cm n=12, 0.5-1cm n=34, 1-2 cm n=28 and >2 cm n=2. CONCLUSION: T2w eMRI cannot exclude prostate cancer with lesions smaller 10mm and 0.4 cm(3) respectively. The detection rate for lesions more than 20mm (1.6 cm(3)) is to be considered as high.
PURPOSE: To evaluate the value of T2w endorectal MRI (eMRI) for correct detection of tumor foci within the prostate regarding tumor size. MATERIALS AND METHODS: 70 patients with histologically proven prostate cancer were examined with T2w eMRI before radical prostatectomy at a 1.5T scanner. For evaluation of eMRI, two radiologists evaluated each tumor focus within the gland. After radical prostatectomy, the prostates were prepared as whole-mount sections, according to transversal T2w eMRI. For each slice, tumor surroundings were marked and compared with eMRI. Based on whole-mount section, 315 slices were evaluated and 533 tumor lesions were documented. RESULTS: Based on the T2w eMRI, 213 tumor lesions were described. In 137/213, histology could prove these lesions. EMRI was able to visualize 0/56 lesions with a maximum size of <0.3 cm (detection rate 0%), between 0.3 and 0.5 cm 4/116 (3%), between 1 and 0.5 cm 22/169 (13%), between 2 and 1cm 61/136 (45%) and for >2 cm 50/56 (89%). False positive eMRI findings were: <0.3 cm n=0, 0.5-0.3 cm n=12, 0.5-1cm n=34, 1-2 cm n=28 and >2 cm n=2. CONCLUSION: T2w eMRI cannot exclude prostate cancer with lesions smaller 10mm and 0.4 cm(3) respectively. The detection rate for lesions more than 20mm (1.6 cm(3)) is to be considered as high.
Authors: M Roethke; A G Anastasiadis; M Lichy; M Werner; P Wagner; S Kruck; Claus D Claussen; A Stenzl; H P Schlemmer; D Schilling Journal: World J Urol Date: 2011-04-22 Impact factor: 4.226
Authors: Matthias C Roethke; Matthias P Lichy; Michaela Kniess; Matthias K Werner; Claus D Claussen; Arnulf Stenzl; Heinz-Peter Schlemmer; David Schilling Journal: World J Urol Date: 2012-01-17 Impact factor: 4.226
Authors: Daniel Junker; Georg Schäfer; Friedrich Aigner; Peter Schullian; Leo Pallwein-Prettner; Jasmin Bektic; Wolfgang Horninger; Ethan J Halpern; Ferdinand Frauscher Journal: ScientificWorldJournal Date: 2012-12-31
Authors: D Junker; T De Zordo; M Quentin; M Ladurner; J Bektic; W Horniger; W Jaschke; F Aigner Journal: Biomed Res Int Date: 2014-05-22 Impact factor: 3.411