BACKGROUND: Suspicious abnormalities seen on screening mammography require further imaging and histologic analysis. Any imaging-histologic discordance necessitates further imaging or surgical excision. METHODS: A retrospective review of all patients with evidence of benign breast lesions having imaging-histologic discordance from January 2005 to December 2007 was compared with the results of a previous study from January 2002 to September 2004. RESULTS: Of 1,264 benign cases, 25 patients had discordance (2%). Surgical intervention was required in 14 of 25 of all discordant cases (56%). One discordant case was found to be malignant after open excision, giving a false-negative rate of 4%. Previous data reported an 8.8% discordance rate, with 65.2% requiring surgical intervention and a false-negative rate of 29.3%. On comparison, the rate of discordance and false-negative image-directed core biopsies were decreased (P<.05). CONCLUSIONS: An organized multidisciplinary approach to imaging-histologic discordance in benign breast disease decreases the rate of discordance and unnecessary surgical interventions. Copyright (c) 2010 Elsevier Inc. All rights reserved.
BACKGROUND: Suspicious abnormalities seen on screening mammography require further imaging and histologic analysis. Any imaging-histologic discordance necessitates further imaging or surgical excision. METHODS: A retrospective review of all patients with evidence of benign breast lesions having imaging-histologic discordance from January 2005 to December 2007 was compared with the results of a previous study from January 2002 to September 2004. RESULTS: Of 1,264 benign cases, 25 patients had discordance (2%). Surgical intervention was required in 14 of 25 of all discordant cases (56%). One discordant case was found to be malignant after open excision, giving a false-negative rate of 4%. Previous data reported an 8.8% discordance rate, with 65.2% requiring surgical intervention and a false-negative rate of 29.3%. On comparison, the rate of discordance and false-negative image-directed core biopsies were decreased (P<.05). CONCLUSIONS: An organized multidisciplinary approach to imaging-histologic discordance in benign breast disease decreases the rate of discordance and unnecessary surgical interventions. Copyright (c) 2010 Elsevier Inc. All rights reserved.
Authors: Daniel N Costa; Fernando U Kay; Ivan Pedrosa; Lauren Kolski; Yair Lotan; Claus G Roehrborn; Brad Hornberger; Yin Xi; Franto Francis; Neil M Rofsky Journal: Urol Oncol Date: 2016-12-09 Impact factor: 3.498
Authors: James Sorace; Denise R Aberle; Dena Elimam; Silvana Lawvere; Ossama Tawfik; W Dean Wallace Journal: BMC Med Date: 2012-09-05 Impact factor: 8.775