Literature DB >> 20221337

The pharmacology of immunosuppression.

Martin M Zdanowicz1.   

Abstract

OBJECTIVE: To provide students with a comprehensive, integrated presentation on the pharmacology of immuosuppression.
DESIGN: Course content on the pharmacology of immunosuppression relating to organ transplantation and treatment of autoimmune disorders was presented in integrated sequence modules that included content from pharmacology, medicinal chemistry, and therapeutics. Weekly recitation sessions and active-learning exercises were incorporated to allow students to apply the information they learned to integrated patient cases and stimulate involvement and critical thinking. Fundamental material related to the components and functions of the immune system was presented to students early in curriculum with courses such as biochemistry, pathophysiology, and immunology/microbiology. ASSESSMENT: Comprehensive examinations, in-class quizzes, written case submissions, case discussions, review exercises, and group exercises were used to assess student learning.
CONCLUSION: Students at South University received a comprehensive and detailed understanding of all aspects relating to immunosuppressive therapy. This was accomplished by integrating instruction on immunosuppressive therapy from various disciplines.

Entities:  

Keywords:  autoimmune disease; immune system; immunosuppression; organ transplantation; pharmacology

Mesh:

Substances:

Year:  2009        PMID: 20221337      PMCID: PMC2828305          DOI: 10.5688/aj7308144

Source DB:  PubMed          Journal:  Am J Pharm Educ        ISSN: 0002-9459            Impact factor:   2.047


  15 in total

Review 1.  Autoimmune diseases.

Authors:  A Davidson; B Diamond
Journal:  N Engl J Med       Date:  2001-08-02       Impact factor: 91.245

Review 2.  The role of cytokine polymorphisms in rejection after solid organ transplantation.

Authors:  S E Marshall; K I Welsh
Journal:  Genes Immun       Date:  2001-10       Impact factor: 2.676

Review 3.  Chronic rejection.

Authors:  P Libby; J S Pober
Journal:  Immunity       Date:  2001-04       Impact factor: 31.745

Review 4.  T-cell allorecognition and transplant rejection: a summary and update.

Authors:  Peter S Heeger
Journal:  Am J Transplant       Date:  2003-05       Impact factor: 8.086

Review 5.  Infection in organ-transplant recipients.

Authors:  J A Fishman; R H Rubin
Journal:  N Engl J Med       Date:  1998-06-11       Impact factor: 91.245

Review 6.  Immunosuppressive drugs: the first 50 years and a glance forward.

Authors:  A C Allison
Journal:  Immunopharmacology       Date:  2000-05

Review 7.  Mechanisms of action of mycophenolate mofetil in preventing acute and chronic allograft rejection.

Authors:  Anthony C Allison; Elsie M Eugui
Journal:  Transplantation       Date:  2005-10-15       Impact factor: 4.939

8.  Interaction of allopurinol with 6-mercaptopurine and azathioprine.

Authors:  R J Brooks; R T Dorr; B G Durie
Journal:  Biomed Pharmacother       Date:  1982       Impact factor: 6.529

Review 9.  Sirolimus: its discovery, biological properties, and mechanism of action.

Authors:  S N Sehgal
Journal:  Transplant Proc       Date:  2003-05       Impact factor: 1.066

Review 10.  Pharmacology of calcineurin antagonists.

Authors:  M H Kapturczak; H U Meier-Kriesche; B Kaplan
Journal:  Transplant Proc       Date:  2004-03       Impact factor: 1.066

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  3 in total

1.  An environmental scan on the status of critical thinking and problem solving skills in colleges/schools of pharmacy: report of the 2009-2010 academic affairs standing committee.

Authors:  Gary M Oderda; Robin M Zavod; Jean T Carter; Johnnie L Early; Pamela U Joyner; Harold Kirschenbaum; Eric J Mack; Andrew P Traynor; Cecilia M Plaza
Journal:  Am J Pharm Educ       Date:  2010-12-15       Impact factor: 2.047

Review 2.  Vaccines: Considerations for pediatric dermatology patients on immunosuppressive agents.

Authors:  Mumtaz A Munshi; Megan H Noe; Yvonne E Chiu; Jenna L Streicher
Journal:  Pediatr Dermatol       Date:  2021-06-01       Impact factor: 1.997

3.  Urinary peptidomic biomarkers of renal function in heart transplant recipients.

Authors:  Qi-Fang Huang; Zhen-Yu Zhang; Jan Van Keer; Sander Trenson; Esther Nkuipou-Kenfack; Wen-Yi Yang; Lutgarde Thijs; Johan Vanhaecke; Lucas N L Van Aelst; Johan Van Cleemput; Stefan Janssens; Peter Verhamme; Harald Mischak; Jan A Staessen
Journal:  Nephrol Dial Transplant       Date:  2019-08-01       Impact factor: 5.992

  3 in total

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