Elisabeth Fernell1, Martina Barnevik-Olsson1, Gunnel Bågenholm1, Christopher Gillberg1, Sven Gustafsson1, Maria Sääf1. 1. .Autism Centre for Young Children, Handicap and Habilitation, Stockholm, Sweden.Unit of Developmental Disorders, Department of Paediatrics, and FoU centre, Skaraborg Hospital, Sweden.PRIMA Child and Adolescent Psychiatry, Stockholm, Sweden.Department of Paediatrics, Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden.Institute of Neuroscience and Physiology, Child and Adolescent Psychiatry, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.Department of Molecular Medicine and Surgery, Karolinska Institute, and Karolinska University Hospital, Stockholm, Sweden.Department of Endocrinology, Karolinska University Hospital, Stockholm, Sweden.
Abstract
AIM: To analyse serum levels of 25-hydroxyvitamin D in mothers of Somali origin and those of Swedish origin who have children with and without autism as there is a growing evidence that low vitamin D impacts adversely on brain development. METHOD: Four groups of mothers were invited to participate; 20 with Somali origin with at least one child with autism, 20 with Somali origin without a child with autism, 20 of Swedish origin with at least one child with autism and 20 with Swedish origin without a child with autism. Two blood samples were collected from each individual; during autumn and spring. RESULTS: Between 12 and 17 mothers from the different groups accepted to participate, both groups of mothers of Somali origin had significantly lower values of 25-hydroxyvitamin D compared with Swedish mothers. The difference of 25-hydroxyvitamin D between mothers of Somali origin with and without a child with autism was not significant. CONCLUSION: Our findings of low vitamin D levels in Somali women entail considerable consequences in a public health perspective. The observed tendency, i.e. the lowest values in mothers of Somali origin with a child with autism was in the predicted direction, supporting the need for further research of vitamin D levels in larger samples of Somali mothers of children with and without autism.
AIM: To analyse serum levels of 25-hydroxyvitamin D in mothers of Somali origin and those of Swedish origin who have children with and without autism as there is a growing evidence that low vitamin D impacts adversely on brain development. METHOD: Four groups of mothers were invited to participate; 20 with Somali origin with at least one child with autism, 20 with Somali origin without a child with autism, 20 of Swedish origin with at least one child with autism and 20 with Swedish origin without a child with autism. Two blood samples were collected from each individual; during autumn and spring. RESULTS: Between 12 and 17 mothers from the different groups accepted to participate, both groups of mothers of Somali origin had significantly lower values of 25-hydroxyvitamin D compared with Swedish mothers. The difference of 25-hydroxyvitamin D between mothers of Somali origin with and without a child with autism was not significant. CONCLUSION: Our findings of low vitamin D levels in Somali women entail considerable consequences in a public health perspective. The observed tendency, i.e. the lowest values in mothers of Somali origin with a child with autism was in the predicted direction, supporting the need for further research of vitamin D levels in larger samples of Somali mothers of children with and without autism.
Authors: Gayle C Windham; Michelle Pearl; Meredith C Anderson; Victor Poon; Darryl Eyles; Karen L Jones; Kristen Lyall; Martin Kharrazi; Lisa A Croen Journal: Autism Res Date: 2019-03-18 Impact factor: 5.216
Authors: Ashraf Z Al-Hamdan; Pooja P Preetha; Reem N Albashaireh; Mohammad Z Al-Hamdan; William L Crosson Journal: Environ Sci Pollut Res Int Date: 2018-01-03 Impact factor: 4.223
Authors: Olga Egorova; Robin Myte; Jörn Schneede; Bruno Hägglöf; Sven Bölte; Erik Domellöf; Barbro Ivars A'roch; Fredrik Elgh; Per Magne Ueland; Sven-Arne Silfverdal Journal: Mol Autism Date: 2020-01-16 Impact factor: 7.509