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Literature DB >> 20215026

Forensic implications of genetic analyses from degraded DNA--a review.

Reza Alaeddini¹, Simon J Walsh, Ali Abbas.

Abstract

Forensic DNA identification techniques are principally based on determination of the size or sequence of desired PCR products. The fragmentation of DNA templates or the structural modifications that can occur during the decomposition process can impact the outcomes of the analytical procedures. This study reviews the pathways involved in cell death and DNA decomposition and the subsequent difficulties these present in DNA analysis of degraded samples. Copyright 2009 Elsevier Ireland Ltd. All rights reserved.

Mesh：

Substances：
DNA

Year: 2009 PMID： 20215026 DOI： 10.1016/j.fsigen.2009.09.007

Source DB: PubMed Journal: Forensic Sci Int Genet ISSN： 1872-4973 Impact factor: 4.882

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Cited

33 in total

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2. Potential relationship between single nucleotide polymorphisms used in forensic genetics and diseases or other traits in European population.

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Journal: Int J Legal Med Date: 2015-03-13 Impact factor: 2.686

Forensic implications of genetic analyses from degraded DNA--a review.

1. The clinical, research, and social value of autopsy after any cancer death: a perspective from the Children's Oncology Group Soft Tissue Sarcoma Committee.

2. Potential relationship between single nucleotide polymorphisms used in forensic genetics and diseases or other traits in European population.

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Review 7. Predicting the fate of eDNA in the environment and implications for studying biodiversity.

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Review 9. Microbial Degradation of Forensic Samples of Biological Origin: Potential Threat to Human DNA Typing.

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