Literature DB >> 20214801

XGAP: a uniform and extensible data model and software platform for genotype and phenotype experiments.

Morris A Swertz1, K Joeri van der Velde, Bruno M Tesson, Richard A Scheltema, Danny Arends, Gonzalo Vera, Rudi Alberts, Martijn Dijkstra, Paul Schofield, Klaus Schughart, John M Hancock, Damian Smedley, Katy Wolstencroft, Carole Goble, Engbert O de Brock, Andrew R Jones, Helen E Parkinson, Ritsert C Jansen.   

Abstract

We present an extensible software model for the genotype and phenotype community, XGAP. Readers can download a standard XGAP (http://www.xgap.org) or auto-generate a custom version using MOLGENIS with programming interfaces to R-software and web-services or user interfaces for biologists. XGAP has simple load formats for any type of genotype, epigenotype, transcript, protein, metabolite or other phenotype data. Current functionality includes tools ranging from eQTL analysis in mouse to genome-wide association studies in humans.

Entities:  

Mesh:

Year:  2010        PMID: 20214801      PMCID: PMC2864567          DOI: 10.1186/gb-2010-11-3-r27

Source DB:  PubMed          Journal:  Genome Biol        ISSN: 1474-7596            Impact factor:   13.583


  55 in total

1.  The generic genome browser: a building block for a model organism system database.

Authors:  Lincoln D Stein; Christopher Mungall; ShengQiang Shu; Michael Caudy; Marco Mangone; Allen Day; Elizabeth Nickerson; Jason E Stajich; Todd W Harris; Adrian Arva; Suzanna Lewis
Journal:  Genome Res       Date:  2002-10       Impact factor: 9.043

Review 2.  Standards for systems biology.

Authors:  Alvis Brazma; Maria Krestyaninova; Ugis Sarkans
Journal:  Nat Rev Genet       Date:  2006-08       Impact factor: 53.242

3.  affyGG: computational protocols for genetical genomics with Affymetrix arrays.

Authors:  Rudi Alberts; Gonzalo Vera; Ritsert C Jansen
Journal:  Bioinformatics       Date:  2007-12-16       Impact factor: 6.937

4.  A genome-wide association study of global gene expression.

Authors:  Anna L Dixon; Liming Liang; Miriam F Moffatt; Wei Chen; Simon Heath; Kenny C C Wong; Jenny Taylor; Edward Burnett; Ivo Gut; Martin Farrall; G Mark Lathrop; Gonçalo R Abecasis; William O C Cookson
Journal:  Nat Genet       Date:  2007-09-16       Impact factor: 38.330

5.  Uncovering regulatory pathways that affect hematopoietic stem cell function using 'genetical genomics'.

Authors:  Leonid Bystrykh; Ellen Weersing; Bert Dontje; Sue Sutton; Mathew T Pletcher; Tim Wiltshire; Andrew I Su; Edo Vellenga; Jintao Wang; Kenneth F Manly; Lu Lu; Elissa J Chesler; Rudi Alberts; Ritsert C Jansen; Robert W Williams; Michael P Cooke; Gerald de Haan
Journal:  Nat Genet       Date:  2005-02-13       Impact factor: 38.330

6.  BioArray Software Environment (BASE): a platform for comprehensive management and analysis of microarray data.

Authors:  Lao H Saal; Carl Troein; Johan Vallon-Christersson; Sofia Gruvberger; Ake Borg; Carsten Peterson
Journal:  Genome Biol       Date:  2002-07-15       Impact factor: 13.583

7.  An analysis of extensible modelling for functional genomics data.

Authors:  Andrew R Jones; Norman W Paton
Journal:  BMC Bioinformatics       Date:  2005-09-27       Impact factor: 3.169

8.  A simple spreadsheet-based, MIAME-supportive format for microarray data: MAGE-TAB.

Authors:  Tim F Rayner; Philippe Rocca-Serra; Paul T Spellman; Helen C Causton; Anna Farne; Ele Holloway; Rafael A Irizarry; Junmin Liu; Donald S Maier; Michael Miller; Kjell Petersen; John Quackenbush; Gavin Sherlock; Christian J Stoeckert; Joseph White; Patricia L Whetzel; Farrell Wymore; Helen Parkinson; Ugis Sarkans; Catherine A Ball; Alvis Brazma
Journal:  BMC Bioinformatics       Date:  2006-11-06       Impact factor: 3.169

9.  Nucleic Acids Research annual Database Issue and the NAR online Molecular Biology Database Collection in 2009.

Authors:  Michael Y Galperin; Guy R Cochrane
Journal:  Nucleic Acids Res       Date:  2008-11-25       Impact factor: 16.971

10.  FlyMine: an integrated database for Drosophila and Anopheles genomics.

Authors:  Rachel Lyne; Richard Smith; Kim Rutherford; Matthew Wakeling; Andrew Varley; Francois Guillier; Hilde Janssens; Wenyan Ji; Peter Mclaren; Philip North; Debashis Rana; Tom Riley; Julie Sullivan; Xavier Watkins; Mark Woodbridge; Kathryn Lilley; Steve Russell; Michael Ashburner; Kenji Mizuguchi; Gos Micklem
Journal:  Genome Biol       Date:  2007       Impact factor: 13.583

View more
  13 in total

1.  The gel electrophoresis markup language (GelML) from the Proteomics Standards Initiative.

Authors:  Frank Gibson; Christine Hoogland; Salvador Martinez-Bartolomé; J Alberto Medina-Aunon; Juan Pablo Albar; Gyorgy Babnigg; Anil Wipat; Henning Hermjakob; Jonas S Almeida; Romesh Stanislaus; Norman W Paton; Andrew R Jones
Journal:  Proteomics       Date:  2010-09       Impact factor: 3.984

Review 2.  Systems genetics in "-omics" era: current and future development.

Authors:  Hong Li
Journal:  Theory Biosci       Date:  2012-11-09       Impact factor: 1.919

3.  Using the Phenogen website for 'in silico' analysis of morphine-induced analgesia: identifying candidate genes.

Authors:  Paula L Hoffman; Beth Bennett; Laura M Saba; Sanjiv V Bhave; Phyllis J Carosone-Link; Cheryl K Hornbaker; Katerina J Kechris; Robert W Williams; Boris Tabakoff
Journal:  Addict Biol       Date:  2010-11-04       Impact factor: 4.280

4.  The MOLGENIS toolkit: rapid prototyping of biosoftware at the push of a button.

Authors:  Morris A Swertz; Martijn Dijkstra; Tomasz Adamusiak; Joeri K van der Velde; Alexandros Kanterakis; Erik T Roos; Joris Lops; Gudmundur A Thorisson; Danny Arends; George Byelas; Juha Muilu; Anthony J Brookes; Engbert O de Brock; Ritsert C Jansen; Helen Parkinson
Journal:  BMC Bioinformatics       Date:  2010-12-21       Impact factor: 3.169

5.  SYSGENET: a meeting report from a new European network for systems genetics.

Authors:  Klaus Schughart
Journal:  Mamm Genome       Date:  2010-07-11       Impact factor: 2.957

6.  VarioML framework for comprehensive variation data representation and exchange.

Authors:  Myles Byrne; Ivo Fac Fokkema; Owen Lancaster; Tomasz Adamusiak; Anni Ahonen-Bishopp; David Atlan; Christophe Béroud; Michael Cornell; Raymond Dalgleish; Andrew Devereau; George P Patrinos; Morris A Swertz; Peter Em Taschner; Gudmundur A Thorisson; Mauno Vihinen; Anthony J Brookes; Juha Muilu
Journal:  BMC Bioinformatics       Date:  2012-10-03       Impact factor: 3.169

7.  OntoCAT--simple ontology search and integration in Java, R and REST/JavaScript.

Authors:  Tomasz Adamusiak; Tony Burdett; Natalja Kurbatova; K Joeri van der Velde; Niran Abeygunawardena; Despoina Antonakaki; Misha Kapushesky; Helen Parkinson; Morris A Swertz
Journal:  BMC Bioinformatics       Date:  2011-05-29       Impact factor: 3.307

Review 8.  Bioinformatics tools and database resources for systems genetics analysis in mice--a short review and an evaluation of future needs.

Authors:  Caroline Durrant; Morris A Swertz; Rudi Alberts; Danny Arends; Steffen Möller; Richard Mott; Pjotr Prins; K Joeri van der Velde; Ritsert C Jansen; Klaus Schughart
Journal:  Brief Bioinform       Date:  2011-07-08       Impact factor: 11.622

9.  xQTL workbench: a scalable web environment for multi-level QTL analysis.

Authors:  Danny Arends; K Joeri van der Velde; Pjotr Prins; Karl W Broman; Steffen Möller; Ritsert C Jansen; Morris A Swertz
Journal:  Bioinformatics       Date:  2012-02-03       Impact factor: 6.937

10.  WormQTL--public archive and analysis web portal for natural variation data in Caenorhabditis spp.

Authors:  L Basten Snoek; K Joeri Van der Velde; Danny Arends; Yang Li; Antje Beyer; Mark Elvin; Jasmin Fisher; Alex Hajnal; Michael O Hengartner; Gino B Poulin; Miriam Rodriguez; Tobias Schmid; Sabine Schrimpf; Feng Xue; Ritsert C Jansen; Jan E Kammenga; Morris A Swertz
Journal:  Nucleic Acids Res       Date:  2012-11-24       Impact factor: 16.971

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.