Literature DB >> 20212932

Treatment of type 2 diabetes in youth: An argument for randomized controlled studies.

H Dean1.   

Abstract

In North America, type 2 diabetes occurs in youth (children and adolescents) of specific ethnic backgrounds, including youth of Aboriginal, Hispanic, Asian, Pacific Islander, Japanese and African-American descent. The treatment of youth with type 2 diabetes represents a unique challenge for paediatricians because of physicians' long experience with this disease in adults but its short history in youth. The education and management of type 2 diabetes in youth must recognize the unique developmental, emotional and social issues associated with this age group, as well as the cultural, linguistic, geographic and socioeconomic issues associated with these populations. With the exception of insulin, the drugs used for adults with type 2 diabetes have not been studied in youth. There is an urgent need for long term, multicentre randomized controlled studies of oral drugs for type 2 diabetes in youth.

Entities:  

Keywords:  Oral antihyperglycemic drugs; Type 2 diabetes

Year:  1999        PMID: 20212932      PMCID: PMC2827719          DOI: 10.1093/pch/4.4.265

Source DB:  PubMed          Journal:  Paediatr Child Health        ISSN: 1205-7088            Impact factor:   2.253


  15 in total

1.  Paediatric pharmacology and toxicology: Drug therapy research for children rather than on children.

Authors:  S M Macleod
Journal:  Paediatr Child Health       Date:  1998-11       Impact factor: 2.253

2.  Diagnostic criteria for non-insulin dependent diabetes in youth (NIDDM-Y).

Authors:  H Dean
Journal:  Clin Pediatr (Phila)       Date:  1998-02       Impact factor: 1.168

3.  Unlicensed and off label drug use in paediatric wards: prospective study.

Authors:  S Turner; A Longworth; A J Nunn; I Choonara
Journal:  BMJ       Date:  1998-01-31

4.  Randomized clinical trial of lifestyle interventions in Pima Indians: a pilot study.

Authors:  K M Narayan; M Hoskin; D Kozak; A M Kriska; R L Hanson; D J Pettitt; D K Nagi; P H Bennett; W C Knowler
Journal:  Diabet Med       Date:  1998-01       Impact factor: 4.359

5.  Diabetic ketoacidosis among obese African-American adolescents with NIDDM.

Authors:  O Pinhas-Hamiel; L M Dolan; P S Zeitler
Journal:  Diabetes Care       Date:  1997-04       Impact factor: 19.112

6.  Increasing prevalence of Type II diabetes in American Indian children.

Authors:  D Dabelea; R L Hanson; P H Bennett; J Roumain; W C Knowler; D J Pettitt
Journal:  Diabetologia       Date:  1998-08       Impact factor: 10.122

Review 7.  1998 clinical practice guidelines for the management of diabetes in Canada. Canadian Diabetes Association.

Authors:  S Meltzer; L Leiter; D Daneman; H C Gerstein; D Lau; S Ludwig; J F Yale; B Zinman; D Lillie
Journal:  CMAJ       Date:  1998       Impact factor: 8.262

8.  U.K. prospective diabetes study 16. Overview of 6 years' therapy of type II diabetes: a progressive disease. U.K. Prospective Diabetes Study Group.

Authors: 
Journal:  Diabetes       Date:  1995-11       Impact factor: 9.461

9.  Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group.

Authors: 
Journal:  Lancet       Date:  1998-09-12       Impact factor: 79.321

10.  Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group.

Authors: 
Journal:  Lancet       Date:  1998-09-12       Impact factor: 79.321

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  4 in total

1.  Healthy active living for children and youth.

Authors: 
Journal:  Paediatr Child Health       Date:  2002-05       Impact factor: 2.253

2.  Type 2 diabetes in First Nation children: A collaborative effort to assess and prevent disease.

Authors:  W Smith; W Gowanlock; K Babcock
Journal:  Paediatr Child Health       Date:  2001-12       Impact factor: 2.253

Review 3.  Type 2 diabetes in children.

Authors:  J H Silverstein; A L Rosenbloom
Journal:  Curr Diab Rep       Date:  2001-08       Impact factor: 4.810

4.  Type 2 diabetes, polycystic ovary syndrome and the insulin resistance syndrome in adolescents: Are they one big iceberg?

Authors:  Heather J Dean; Elizabeth Ac Sellers
Journal:  Paediatr Child Health       Date:  2002-05       Impact factor: 2.253

  4 in total

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