| Literature DB >> 20211144 |
Sinésio Talhari1, Mônica Nunes de Souza Santos, Carolina Talhari, Luiz Carlos de Lima Ferreira, Roberto Moreira Silva, Bernhard Zelger, Cesare Massone, Rodrigo Ribeiro-Rodrigues.
Abstract
In the present study, we report the occurrence of Lyme's borreliosis in patients from the Brazilian Amazon Region. Borreliosis was investigated by immunohistochemistry and focus floating microscopy for Borrelia burgdorferi in skin biopsy samples from 22 patients with both clinical and histopathology evidences compatible with Erythema Migrans. Spirochetes were detected by specific immunohistochemistry and focus floating microscopy for B. burgdorferi in samples from five patients. Clinical cure of the cutaneous lesions was observed in all the patients after treatment with doxycycline regimen as proposed by the Center Disease Control guidelines. A limitation of our study was the fact that we were not able to isolate and culture these organisms. These are the first known Brazilian cases of borreliosis to have Focus Floating Microscopy confirmation. 2010 Elsevier B.V. All rights reserved.Entities:
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Year: 2010 PMID： 20211144 DOI： 10.1016/j.actatropica.2010.02.017
Source DB: PubMed Journal: Acta Trop ISSN： 0001-706X Impact factor: 3.112