Literature DB >> 20208375

Pro-oxidant action of pyrroloquinoline quinone: characterization of protein oxidative modifications.

Takeshi Ishii1, Mitsugu Akagawa, Yuji Naito, Osamu Handa, Tomohisa Takagi, Taiki Mori, Shigenori Kumazawa, Toshikazu Yoshikawa, Tsutomu Nakayama.   

Abstract

Pyrroloquinoline quinone (PQQ), a putative essential nutrient, is a redox modulator in cell and animal models. Here we characterized PQQ-induced protein oxidative modifications in a model peptide and protein, and we propose that the mechanism of protein modification by PQQ is redox cycling-mediated oxidation. PQQ may contribute to the regulation of intracellular protein functions through its prooxidant action.

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Year:  2010        PMID： 20208375     DOI： 10.1271/bbb.90764

Source DB:  PubMed          Journal:  Biosci Biotechnol Biochem        ISSN： 0916-8451            Impact factor:   2.043


  7 in total

1.  Biological effects of pyrroloquinoline quinone on liver damage in Bmi-1 knockout mice.

Authors:  Yuanqing Huang; Ning Chen; Dengshun Miao
Journal:  Exp Ther Med       Date:  2015-05-29       Impact factor: 2.447

2.  Effect and mechanism of pyrroloquinoline quinone on anti-osteoporosis in Bmi-1 knockout mice-Anti-oxidant effect of pyrroloquinoline quinone.

Authors:  Yuanqing Huang; Ning Chen; Dengshun Miao
Journal:  Am J Transl Res       Date:  2017-10-15       Impact factor: 4.060

3.  Attenuation of adjuvant-induced arthritis by dietary sesamol via modulation of inflammatory mediators, extracellular matrix degrading enzymes and antioxidant status.

Authors:  Mahadevappa Hemshekhar; Ram Mohan Thushara; Sadashivaiah Jnaneshwari; Sannaningaiah Devaraja; Kempaiah Kemparaju; Kesturu Subbaiah Girish
Journal:  Eur J Nutr       Date:  2012-12-27       Impact factor: 5.614

4.  Radioprotective effects of pyrroloquinoline quinone on parotid glands in C57BL/6J mice.

Authors:  Yuanqing Huang; Ning Chen; Dengshun Miao
Journal:  Exp Ther Med       Date:  2016-10-26       Impact factor: 2.447

5.  Fermented Wheat Germ Extract as a Redox Modulator: Alleviating Endotoxin-Triggered Oxidative Stress in Primary Cultured Rat Hepatocytes.

Authors:  Máté Mackei; Júlia Vörösházi; Csilla Sebők; Zsuzsanna Neogrády; Gábor Mátis; Ákos Jerzsele
Journal:  Oxid Med Cell Longev       Date:  2020-12-08       Impact factor: 6.543

6.  Identification of transcriptional networks responding to pyrroloquinoline quinone dietary supplementation and their influence on thioredoxin expression, and the JAK/STAT and MAPK pathways.

Authors:  Eskouhie Tchaparian; Lisa Marshal; Gene Cutler; Kathryn Bauerly; Winyoo Chowanadisai; Michael Satre; Calliandra Harris; Robert B Rucker
Journal:  Biochem J       Date:  2010-08-01       Impact factor: 3.857

7.  Role of the ubiquitin-proteasome system in cardiac dysfunction of adipose triglyceride lipase-deficient mice.

Authors:  Marion Mussbacher; Heike Stessel; Gerald Wölkart; Guenter Haemmerle; Rudolf Zechner; Bernd Mayer; Astrid Schrammel
Journal:  J Mol Cell Cardiol       Date:  2014-10-05       Impact factor: 5.000
  7 in total

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