| Literature DB >> 20207167 |
Mark S Slaughter1, Michael S Ising, Daniel Tamez, Gerry O'Driscoll, Neil Voskoboynikov, Carlo R Bartoli, Steven C Koenig, Guruprasad A Giridharan.
Abstract
The circadian rhythm of varying blood pressure and heart rate is attenuated or absent in patients with severe heart failure. In 28 patients supported by a left ventricular assist device (LVAD) for at least 30 days, a restoration of the circadian rhythm was demonstrated by a consistent nocturnal decrease, and then increase, of the LVAD flow while at a constant LVAD speed. The return of the circadian rhythm has implications for cardiac recovery, and the observation indicates that the continuous-flow LVAD has an intrinsic automatic response to physiologic demands. Copyright 2010 International Society for Heart and Lung Transplantation. Published by Elsevier Inc. All rights reserved.Entities:
Mesh:
Year: 2010 PMID: 20207167 PMCID: PMC3810018 DOI: 10.1016/j.healun.2009.12.006
Source DB: PubMed Journal: J Heart Lung Transplant ISSN: 1053-2498 Impact factor: 10.247