OBJECTIVE: Oesophageal gastrointestinal stromal tumours (GISTs) are extremely rare. The preoperative diagnosis is complicated by lack of specificity and the clinical features of patients with oesophageal GISTs need to be fully studied. METHODS: We have reviewed retrospectively the medical records of those patients who are treated surgically for oesophageal GISTs in our two hospitals. RESULTS: Eight oesophageal GISTs were identified among the 63 oesophageal mesenchymal tumours in our two hospitals in the past 30 years. Of the eight patients, the male:female ratio was 5:3; the median age of the patients was 57 years (range 49-71 years). Dysphagia was the most common symptom, and all cases were diagnosed postoperatively. The tumours were resected by enucleation or oesophagectomy. The median follow-up was 59 months, ranging from 14 to 202 months, with four of the patients succumbing to the disease, among them two with recurrence and another two with metastasis. CONCLUSIONS: Our study indicates that oesophageal GIST is rather rare, and it has relatively high recurrence and mortality rates, especially for patients with large tumours (larger than 9 cm). At present, surgical resection and postoperative diagnosis remain the mainstay for treatment of patients with oesophageal GISTs in China. Copyright 2010 European Association for Cardio-Thoracic Surgery. Published by Elsevier B.V. All rights reserved.
OBJECTIVE:Oesophageal gastrointestinal stromal tumours (GISTs) are extremely rare. The preoperative diagnosis is complicated by lack of specificity and the clinical features of patients with oesophageal GISTs need to be fully studied. METHODS: We have reviewed retrospectively the medical records of those patients who are treated surgically for oesophageal GISTs in our two hospitals. RESULTS: Eight oesophageal GISTs were identified among the 63 oesophageal mesenchymal tumours in our two hospitals in the past 30 years. Of the eight patients, the male:female ratio was 5:3; the median age of the patients was 57 years (range 49-71 years). Dysphagia was the most common symptom, and all cases were diagnosed postoperatively. The tumours were resected by enucleation or oesophagectomy. The median follow-up was 59 months, ranging from 14 to 202 months, with four of the patients succumbing to the disease, among them two with recurrence and another two with metastasis. CONCLUSIONS: Our study indicates that oesophageal GIST is rather rare, and it has relatively high recurrence and mortality rates, especially for patients with large tumours (larger than 9 cm). At present, surgical resection and postoperative diagnosis remain the mainstay for treatment of patients with oesophageal GISTs in China. Copyright 2010 European Association for Cardio-Thoracic Surgery. Published by Elsevier B.V. All rights reserved.
Authors: Simon Lott; Michael Schmieder; Benjamin Mayer; Doris Henne-Bruns; Uwe Knippschild; Abbas Agaimy; Matthias Schwab; Klaus Kramer Journal: Am J Cancer Res Date: 2014-12-15 Impact factor: 6.166
Authors: A B Shinagare; K A Zukotynski; K M Krajewski; J P Jagannathan; J Butrynski; J L Hornick; N H Ramaiya Journal: Cancer Imaging Date: 2012-04-27 Impact factor: 3.909
Authors: Kyriakos Neofytou; Mafalda Costa Neves; Alexandros Giakoustidis; Charlotte Benson; Satvinder Mudan Journal: Case Rep Oncol Med Date: 2015-05-05
Authors: Charalampos G Markakis; Eleftherios D Spartalis; Emmanouil Liarmakopoulos; Evangelia G Kavoura; Periklis Tomos Journal: Case Rep Surg Date: 2013-04-30