Literature DB >> 20194693

Efflux pumps, OprD porin, AmpC beta-lactamase, and multiresistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients.

Maria Tomás1, Michel Doumith, Marina Warner, Jane F Turton, Alejandro Beceiro, German Bou, David M Livermore, Neil Woodford.   

Abstract

Expression of ampC, oprD, mexA, mexC, mexE, and mexX was studied in 25 Pseudomonas aeruginosa isolates from cystic fibrosis patients, including 14 isolates of the Liverpool epidemic strain. Overexpressed mexA or ampC and reduced oprD were associated with beta-lactam resistance. A specific combination of mexR, nalC, and nalD mutations occurred in 11 Liverpool strain isolates, including 7 with upregulated mexA.

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Year:  2010        PMID： 20194693      PMCID： PMC2863613          DOI： 10.1128/AAC.00816-09

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  31 in total

1.  Multiplex PCR for rapid detection of genes encoding acquired metallo-beta-lactamases.

Authors:  Matthew J Ellington; James Kistler; David M Livermore; Neil Woodford
Journal:  J Antimicrob Chemother       Date:  2006-12-21       Impact factor: 5.790

2.  Genetic adaptation by Pseudomonas aeruginosa to the airways of cystic fibrosis patients.

Authors:  Eric E Smith; Danielle G Buckley; Zaining Wu; Channakhone Saenphimmachak; Lucas R Hoffman; David A D'Argenio; Samuel I Miller; Bonnie W Ramsey; David P Speert; Samuel M Moskowitz; Jane L Burns; Rajinder Kaul; Maynard V Olson
Journal:  Proc Natl Acad Sci U S A       Date:  2006-05-10       Impact factor: 11.205

3.  Interplay of efflux system, ampC, and oprD expression in carbapenem resistance of Pseudomonas aeruginosa clinical isolates.

Authors:  John Quale; Simona Bratu; Jyoti Gupta; David Landman
Journal:  Antimicrob Agents Chemother       Date:  2006-05       Impact factor: 5.191

4.  Involvement of an active efflux system in the natural resistance of Pseudomonas aeruginosa to aminoglycosides.

Authors:  J R Aires; T Köhler; H Nikaido; P Plésiat
Journal:  Antimicrob Agents Chemother       Date:  1999-11       Impact factor: 5.191

5.  Characterization of poxB, a chromosomal-encoded Pseudomonas aeruginosa oxacillinase.

Authors:  Kok-Fai Kong; Suriya R Jayawardena; Aimee Del Puerto; Lutz Wiehlmann; Ulrike Laabs; Burkhard Tümmler; Kalai Mathee
Journal:  Gene       Date:  2005-09-26       Impact factor: 3.688

6.  Mutations in PA3574 (nalD) lead to increased MexAB-OprM expression and multidrug resistance in laboratory and clinical isolates of Pseudomonas aeruginosa.

Authors:  Mara L Sobel; Didier Hocquet; Lily Cao; Patrick Plesiat; Keith Poole
Journal:  Antimicrob Agents Chemother       Date:  2005-05       Impact factor: 5.191

7.  Carbapenem activities against Pseudomonas aeruginosa: respective contributions of OprD and efflux systems.

Authors:  T Köhler; M Michea-Hamzehpour; S F Epp; J C Pechere
Journal:  Antimicrob Agents Chemother       Date:  1999-02       Impact factor: 5.191

8.  Role of efflux pump(s) in intrinsic resistance of Pseudomonas aeruginosa: resistance to tetracycline, chloramphenicol, and norfloxacin.

Authors:  X Z Li; D M Livermore; H Nikaido
Journal:  Antimicrob Agents Chemother       Date:  1994-08       Impact factor: 5.191

9.  Role of efflux pump(s) in intrinsic resistance of Pseudomonas aeruginosa: active efflux as a contributing factor to beta-lactam resistance.

Authors:  X Z Li; D Ma; D M Livermore; H Nikaido
Journal:  Antimicrob Agents Chemother       Date:  1994-08       Impact factor: 5.191

10.  Evaluation of methods to identify the Klebsiella pneumoniae carbapenemase in Enterobacteriaceae.

Authors:  K F Anderson; D R Lonsway; J K Rasheed; J Biddle; B Jensen; L K McDougal; R B Carey; A Thompson; S Stocker; B Limbago; J B Patel
Journal:  J Clin Microbiol       Date:  2007-06-20       Impact factor: 5.948
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  58 in total

1.  Bactericidal activities of cathelicidin LL-37 and select cationic lipids against the hypervirulent Pseudomonas aeruginosa strain LESB58.

Authors:  Urszula Wnorowska; Katarzyna Niemirowicz; Melissa Myint; Scott L Diamond; Marta Wróblewska; Paul B Savage; Paul A Janmey; Robert Bucki
Journal:  Antimicrob Agents Chemother       Date:  2015-04-13       Impact factor: 5.191

2.  Quorum quenching quandary: resistance to antivirulence compounds.

Authors:  Toshinari Maeda; Rodolfo García-Contreras; Mingming Pu; Lili Sheng; Luis Rene Garcia; Maria Tomás; Thomas K Wood
Journal:  ISME J       Date:  2011-09-15       Impact factor: 10.302

3.  Antimicrobial Effect of Imipenem-Functionalized Fe2O3 Nanoparticles on Pseudomonas aeruginosa Producing Metallo β-lactamases.

Authors:  Mohammad Reza Khataminejad; Reza Mirnejad; Malike Sharif; Mojtaba Hashemi; Nikita Sajadi; Vahhab Piranfar
Journal:  Iran J Biotechnol       Date:  2015-12       Impact factor: 1.671

Review 4.  The challenge of efflux-mediated antibiotic resistance in Gram-negative bacteria.

Authors:  Xian-Zhi Li; Patrick Plésiat; Hiroshi Nikaido
Journal:  Clin Microbiol Rev       Date:  2015-04       Impact factor: 26.132

Review 5.  Adaptive and mutational resistance: role of porins and efflux pumps in drug resistance.

Authors:  Lucía Fernández; Robert E W Hancock
Journal:  Clin Microbiol Rev       Date:  2012-10       Impact factor: 26.132

Review 6.  Exploiting quorum sensing to confuse bacterial pathogens.

Authors:  Breah LaSarre; Michael J Federle
Journal:  Microbiol Mol Biol Rev       Date:  2013-03       Impact factor: 11.056

Review 7.  Antimicrobial resistance and virulence: a successful or deleterious association in the bacterial world?

Authors:  Alejandro Beceiro; María Tomás; Germán Bou
Journal:  Clin Microbiol Rev       Date:  2013-04       Impact factor: 26.132

8.  Identification of novel genes responsible for overexpression of ampC in Pseudomonas aeruginosa PAO1.

Authors:  Yuko Tsutsumi; Haruyoshi Tomita; Koichi Tanimoto
Journal:  Antimicrob Agents Chemother       Date:  2013-09-16       Impact factor: 5.191

9.  Antimicrobial Susceptibility of Pseudomonas aeruginosa Isolated from Cystic Fibrosis Patients in Northern Europe.

Authors:  Muhammad-Hariri Mustafa; Hussein Chalhoub; Olivier Denis; Ariane Deplano; Anne Vergison; Hector Rodriguez-Villalobos; Michael M Tunney; J Stuart Elborn; Barbara C Kahl; Hamidou Traore; Francis Vanderbist; Paul M Tulkens; Françoise Van Bambeke
Journal:  Antimicrob Agents Chemother       Date:  2016-10-21       Impact factor: 5.191

10.  Efflux pumps expression and its association with porin down-regulation and beta-lactamase production among Pseudomonas aeruginosa causing bloodstream infections in Brazil.

Authors:  Danilo E Xavier; Renata C Picão; Raquel Girardello; Lorena C C Fehlberg; Ana C Gales
Journal:  BMC Microbiol       Date:  2010-08-12       Impact factor: 3.605
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