Literature DB >> 20192207

Conversion of 4,4-difluoro-4-bora-3a,4a-diaza-s-indacenes (F-BODIPYs) to dipyrrins with a microwave-promoted deprotection strategy.

Sarah M Crawford1, Alison Thompson.   

Abstract

4,4-Difluoro-4-bora-3a,4a-diaza-s-indacenes (F-BODIPYs) have been deprotected to give the corresponding free-base dipyrrins by heating a solution of the F-BODIPY in tert-butanol under 600 W of microwave irradiation in the presence of 6 equiv of potassium tert-butoxide for 40 min at 92 degrees C. Investigations of BODIPY modification at the meso position have also been undertaken and a meso-butyl product has been isolated.

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Year:  2010        PMID： 20192207     DOI： 10.1021/ol902908j

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  4 in total

1.  Development of a multi faceted platform containing a tetrazine, fluorophore and chelator: synthesis, characterization, radiolabeling, and immuno-SPECT imaging.

Authors:  Anthony W McDonagh; Brooke L McNeil; Julie Rousseau; Ryan J Roberts; Helen Merkens; Hua Yang; François Bénard; Caterina F Ramogida
Journal:  EJNMMI Radiopharm Chem       Date:  2022-06-06

2.  Efficient deprotection of F-BODIPY derivatives: removal of BF2 using Brønsted acids.

Authors:  Mingfeng Yu; Joseph K-H Wong; Cyril Tang; Peter Turner; Matthew H Todd; Peter J Rutledge
Journal:  Beilstein J Org Chem       Date:  2015-01-09       Impact factor: 2.883

3.  Syntheses and Investigations of Conformationally Restricted, Linker-Free α-Amino Acid-BODIPYs via Boron Functionalization.

Authors:  Maodie Wang; Guanyu Zhang; Petia Bobadova-Parvanova; Kevin M Smith; M Graça H Vicente
Journal:  J Org Chem       Date:  2021-11-22       Impact factor: 4.354

4.  Facile deprotection of F-BODIPYs using methylboronic acid.

Authors:  Craig D Smith; Alison Thompson
Journal:  RSC Adv       Date:  2020-06-25       Impact factor: 4.036
  4 in total

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