Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 GENE AND CELL THERAPY FOR LIFE-THREATENING CARDIAC ARRHYTHMIAS.

Literature DB >> 20191107

GENE AND CELL THERAPY FOR LIFE-THREATENING CARDIAC ARRHYTHMIAS.

Michael R Rosen, Peter Danilo, Richard B Robinson.

Abstract

Gene and cell therapies of cardiac arrhythmias are nascent fields whose raison d'etre derives from (1) the problematic state of arrhythmia treatment today (especially atrial and ventricular tachyarrhythmias for which drugs, devices and ablation remain more stopgaps then optimal interventions), and (2) the opportunity to learn and potentially treat and cure by exploring new technologies. The state of antiarrhythmic therapy and new directions being taken are reviewed.

Entities: Chemical Disease Gene Mutation Species

Year: 2009 PMID： 20191107 PMCID： PMC2828741

Source DB: PubMed Journal: Dialog Cardiovasc Med ISSN： 1272-9949

29 in total

1. Coronary perfusion cocktails for in vivo gene transfer.

Authors: Stephan E Lehnart; J Kevin Donahue
Journal: Methods Mol Biol Date: 2003

2. Posttranslational control of a cardiac ion channel transgene in vivo: clarithromycin-hMiRP1-Q9E interactions.

Authors: Itay Perlstein; Denise Y Burton; Kenneth Ryan; Suzanne Defelice; Erin Simmers; Barry Campbell; Jeanne M Connolly; Amnon Hoffman; Robert J Levy
Journal: Hum Gene Ther Date: 2005-07 Impact factor: 5.695

Review 3. Emerging role for bone marrow derived mesenchymal stem cells in myocardial regenerative therapy.

Authors: Jeffrey M Zimmet; Joshua M Hare
Journal: Basic Res Cardiol Date: 2005-11 Impact factor: 17.165

4. Secular trends in incidence of atrial fibrillation in Olmsted County, Minnesota, 1980 to 2000, and implications on the projections for future prevalence.

Authors: Yoko Miyasaka; Marion E Barnes; Bernard J Gersh; Stephen S Cha; Kent R Bailey; Walter P Abhayaratna; James B Seward; Teresa S M Tsang
Journal: Circulation Date: 2006-07-03 Impact factor: 29.690

5. Circus movement in rabbit atrial muscle as a mechanism of tachycardia. III. The "leading circle" concept: a new model of circus movement in cardiac tissue without the involvement of an anatomical obstacle.

Authors: M A Allessie; F I Bonke; F J Schopman
Journal: Circ Res Date: 1977-07 Impact factor: 17.367

6. The consequences of disrupting cardiac inwardly rectifying K(+) current (I(K1)) as revealed by the targeted deletion of the murine Kir2.1 and Kir2.2 genes.

Authors: J J Zaritsky; J B Redell; B L Tempel; T L Schwarz
Journal: J Physiol Date: 2001-06-15 Impact factor: 5.182

Review 7. New approaches to antiarrhythmic therapy; emerging therapeutic applications of the cell biology of cardiac arrhythmias.

Authors:
Journal: Eur Heart J Date: 2001-12 Impact factor: 29.983

GENE AND CELL THERAPY FOR LIFE-THREATENING CARDIAC ARRHYTHMIAS.

1. Coronary perfusion cocktails for in vivo gene transfer.

2. Posttranslational control of a cardiac ion channel transgene in vivo: clarithromycin-hMiRP1-Q9E interactions.

Review 3. Emerging role for bone marrow derived mesenchymal stem cells in myocardial regenerative therapy.

4. Secular trends in incidence of atrial fibrillation in Olmsted County, Minnesota, 1980 to 2000, and implications on the projections for future prevalence.

5. Circus movement in rabbit atrial muscle as a mechanism of tachycardia. III. The "leading circle" concept: a new model of circus movement in cardiac tissue without the involvement of an anatomical obstacle.

6. The consequences of disrupting cardiac inwardly rectifying K(+) current (I(K1)) as revealed by the targeted deletion of the murine Kir2.1 and Kir2.2 genes.

Review 7. New approaches to antiarrhythmic therapy; emerging therapeutic applications of the cell biology of cardiac arrhythmias.

8. Overexpression of cardiac connexin45 increases susceptibility to ventricular tachyarrhythmias in vivo.

9. Molecular ablation of ventricular tachycardia after myocardial infarction.

10. Electromechanical integration of cardiomyocytes derived from human embryonic stem cells.

Review 1. Regenerative therapies in electrophysiology and pacing: introducing the next steps.

2. Cell and gene therapy for arrhythmias: Repair of cardiac conduction damage.

3. Cardiac arrhythmia and heart failure: From bench to bedside.