Literature DB >> 20190828

PTH battles TGF-beta in bone.

Azeddine Atfi1, Roland Baron.   

Abstract

Bone remodelling in vertebrates is coordinately regulated by the opposing effects of parathyroid hormone (PTH) and transforming growth factor-beta (TGF-beta). PTH couples the processes of bone resorption and formation by enforcing simultaneous internalization of TGF-beta type II receptor (TbetaRII) and PTH type 1 receptor (PTH1R), which attenuates both TGF-beta and PTH signalling in vivo.

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Year:  2010        PMID： 20190828     DOI： 10.1038/ncb0310-205

Source DB:  PubMed          Journal:  Nat Cell Biol        ISSN： 1465-7392            Impact factor:   28.824


  14 in total

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Authors:  Yigong Shi; Joan Massagué
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Review 2.  Seven-transmembrane receptors.

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Review 3.  Skeletal remodeling in health and disease.

Authors:  Mone Zaidi
Journal:  Nat Med       Date:  2007-07       Impact factor: 53.440

4.  Parathyroid hormone signaling through low-density lipoprotein-related protein 6.

Authors:  Mei Wan; Chaozhe Yang; Jun Li; Xiangwei Wu; Hongling Yuan; Hairong Ma; Xi He; Shuyi Nie; Chenbei Chang; Xu Cao
Journal:  Genes Dev       Date:  2008-11-01       Impact factor: 11.361

5.  Activated parathyroid hormone/parathyroid hormone-related protein receptor in osteoblastic cells differentially affects cortical and trabecular bone.

Authors:  L M Calvi; N A Sims; J L Hunzelman; M C Knight; A Giovannetti; J M Saxton; H M Kronenberg; R Baron; E Schipani
Journal:  J Clin Invest       Date:  2001-02       Impact factor: 14.808

6.  TGF-beta-induced repression of CBFA1 by Smad3 decreases cbfa1 and osteocalcin expression and inhibits osteoblast differentiation.

Authors:  T Alliston; L Choy; P Ducy; G Karsenty; R Derynck
Journal:  EMBO J       Date:  2001-05-01       Impact factor: 11.598

7.  TGF-beta type II receptor phosphorylates PTH receptor to integrate bone remodelling signalling.

Authors:  Tao Qiu; Xiangwei Wu; Fengjie Zhang; Thomas L Clemens; Mei Wan; Xu Cao
Journal:  Nat Cell Biol       Date:  2010-02-07       Impact factor: 28.824

Review 8.  p53 brings a new twist to the Smad signaling network.

Authors:  Azeddine Atfi; Roland Baron
Journal:  Sci Signal       Date:  2008-07-01       Impact factor: 8.192

Review 9.  The cell biology of parathyroid hormone in osteoblasts.

Authors:  Stavroula Kousteni; John P Bilezikian
Journal:  Curr Osteoporos Rep       Date:  2008-06       Impact factor: 5.096

Review 10.  Parathyroid hormone: a double-edged sword for bone metabolism.

Authors:  Ling Qin; Liza J Raggatt; Nicola C Partridge
Journal:  Trends Endocrinol Metab       Date:  2004-03       Impact factor: 12.015
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  9 in total

1.  Inhibition of Sca-1-positive skeletal stem cell recruitment by alendronate blunts the anabolic effects of parathyroid hormone on bone remodeling.

Authors:  Xiangwei Wu; Lijuan Pang; Weiqi Lei; William Lu; Jun Li; Zhaoyang Li; Frank J Frassica; Xueling Chen; Mei Wan; Xu Cao
Journal:  Cell Stem Cell       Date:  2010-11-05       Impact factor: 24.633

2.  A review of the efficacy and safety of denosumab in postmenopausal women with osteoporosis.

Authors:  Paul D Miller
Journal:  Ther Adv Musculoskelet Dis       Date:  2011-12       Impact factor: 5.346

Review 3.  Regulation of Bone Remodeling by Parathyroid Hormone.

Authors:  Marc N Wein; Henry M Kronenberg
Journal:  Cold Spring Harb Perspect Med       Date:  2018-08-01       Impact factor: 6.915

4.  Activation of Parathyroid Hormone 2 Receptor Induces Decorin Expression and Promotes Wound Repair.

Authors:  Emi Sato; Ling-Juan Zhang; Robert A Dorschner; Christopher A Adase; Biswa P Choudhury; Richard L Gallo
Journal:  J Invest Dermatol       Date:  2017-04-26       Impact factor: 8.551

5.  Prolonged alendronate treatment prevents the decline in serum TGF-β1 levels and reduces cortical bone strength in long-term estrogen deficiency rat model.

Authors:  Junjing Jia; Wei Yao; Sarah Amugongo; Mohammad Shahnazari; Weiwei Dai; Yu-An E Lay; Diana Olvera; Elizabeth A Zimmermann; Robert O Ritchie; Chin-Shang Li; Tamara Alliston; Nancy E Lane
Journal:  Bone       Date:  2012-10-23       Impact factor: 4.398

Review 6.  TGF-β and BMP signaling in osteoblast differentiation and bone formation.

Authors:  Guiqian Chen; Chuxia Deng; Yi-Ping Li
Journal:  Int J Biol Sci       Date:  2012-01-21       Impact factor: 6.580

7.  Bisphosphonate Modulation of the Gene Expression of Different Markers Involved in Osteoblast Physiology: Possible Implications in Bisphosphonate-Related Osteonecrosis of the Jaw.

Authors:  Francisco Javier Manzano-Moreno; Javier Ramos-Torrecillas; Lucia Melguizo-Rodríguez; Rebeca Illescas-Montes; Concepción Ruiz; Olga García-Martínez
Journal:  Int J Med Sci       Date:  2018-02-12       Impact factor: 3.738

8.  Simulated Interventions to Ameliorate Age-Related Bone Loss Indicate the Importance of Timing.

Authors:  Carole J Proctor; Alison Gartland
Journal:  Front Endocrinol (Lausanne)       Date:  2016-06-13       Impact factor: 5.555

Review 9.  TGF-β and BMP signaling in osteoblast, skeletal development, and bone formation, homeostasis and disease.

Authors:  Mengrui Wu; Guiqian Chen; Yi-Ping Li
Journal:  Bone Res       Date:  2016-04-26       Impact factor: 13.567
  9 in total

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