Literature DB >> 20188427

Single Arc Volumetric Modulated Arc Therapy of head and neck cancer.

Anders Bertelsen1, Christian R Hansen, Jørgen Johansen, Carsten Brink.   

Abstract

BACKGROUND: The quality of Volumetric Modulated Arc Therapy (VMAT) plans is highly dependent on the performance of the optimization algorithm used. Recently new algorithms have become available which are capable of generating VMAT plans for Elekta accelerators. The VMAT algorithm in Pinnacle is named SmartArc and its capability to generate treatment plans for head and neck cancer was tested.
METHODS: Twenty-five patients with oropharyngeal or hypopharyngeal carcinoma, previously treated with IMRT by means of Pinnacle and Elekta accelerators, were replanned with single arc VMAT. The VMAT planning objectives were to achieve clinical target coverage and sparing of the organs at risk (OAR). Comparison with the original clinically used IMRT was made by evaluating (1) dose-volume histograms (DVHs) for PTVs, (2) DVHs for OARs, (3) delivery time and monitor units (MU), and (4) treatment accuracy.
RESULTS: Equivalent or superior target coverage and sparing of OARs were achieved with VMAT compared to IMRT. Volumes in the healthy tissues receiving between 17.3 Gy and 49.4 Gy were significantly reduced and the conformity (CI(95%)) of the elective PTV was improved from 1.7 with IMRT to 1.6 with VMAT. Compared to step-and-shoot IMRT, VMAT reduced the number of MUs by 8.5% to 460+/-63 MUs per fraction, and delivered on an Elekta Synergy accelerator, the treatment time was on average reduced by 35% to 241 +/- 16s. In Delta4 measurements of the VMAT treatments, 99.6 +/- 0.5% of the detector points passed a 3 mm and 3% gamma criterion, identical to the results of IMRT.
CONCLUSIONS: The target coverages obtained in the IMRT and VMAT plans were found to be very similar. SmartArc generated single arc VMAT plans with equivalent or better target coverage and sparing of OARs compared to IMRT, while both delivery time and MUs were decreased. Very good dose accuracy results were obtained delivering the plans on an Elekta accelerator. Copyright 2010 Elsevier Ireland Ltd. All rights reserved.

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Year:  2010        PMID: 20188427     DOI: 10.1016/j.radonc.2010.01.011

Source DB:  PubMed          Journal:  Radiother Oncol        ISSN: 0167-8140            Impact factor:   6.280


  71 in total

1.  Comparative analysis of SmartArc-based dual arc volumetric-modulated arc radiotherapy (VMAT) versus intensity-modulated radiotherapy (IMRT) for nasopharyngeal carcinoma.

Authors:  Tsair-Fwu Lee; Pei-Ju Chao; Hui-Min Ting; Su-Hua Lo; Yu-Wen Wang; Chiu-Ching Tuan; Fu-Min Fang; Te-Jen Su
Journal:  J Appl Clin Med Phys       Date:  2011-11-15       Impact factor: 2.102

Review 2.  Volumetric modulated arc therapy: a review of current literature and clinical use in practice.

Authors:  M Teoh; C H Clark; K Wood; S Whitaker; A Nisbet
Journal:  Br J Radiol       Date:  2011-11       Impact factor: 3.039

3.  Effect of photon-beam energy on VMAT and IMRT treatment plan quality and dosimetric accuracy for advanced prostate cancer.

Authors:  Marlies Pasler; Dietmar Georg; Holger Wirtz; Johannes Lutterbach
Journal:  Strahlenther Onkol       Date:  2011-11-29       Impact factor: 3.621

4.  A prospective trial of volumetric intensity-modulated arc therapy vs conventional intensity modulated radiation therapy in advanced head and neck cancer.

Authors:  Simon D Fung-Kee-Fung; Rachel Hackett; Lee Hales; Graham Warren; Anurag K Singh
Journal:  World J Clin Oncol       Date:  2012-04-10

5.  Penalization of aperture complexity in inversely planned volumetric modulated arc therapy.

Authors:  Kelly C Younge; Martha M Matuszak; Jean M Moran; Daniel L McShan; Benedick A Fraass; Donald A Roberts
Journal:  Med Phys       Date:  2012-11       Impact factor: 4.071

6.  Evaluation of the trade-offs encountered in planning and treating locally advanced head and neck cancer: intensity-modulated radiation therapy vs dual-arc volumetric-modulated arc therapy.

Authors:  M Oliver; D McConnell; M Romani; A McAllister; A Pearce; A Andronowski; X Wang; K Leszczynski
Journal:  Br J Radiol       Date:  2012-07-17       Impact factor: 3.039

7.  Impact of machines on plan quality: volumetric modulated arc therapy and intensity modulated radiation therapy.

Authors:  S Clemente; M Cozzolino; C Oliviero; A Fiorentino; C Chiumento; V Fusco
Journal:  Clin Transl Oncol       Date:  2013-05-04       Impact factor: 3.405

8.  The impact of direct aperture optimization on plan quality and efficiency in complex head and neck IMRT.

Authors:  Marcello Sabatino; Matthias Kretschmer; Klemens Zink; Florian Würschmidt
Journal:  Radiat Oncol       Date:  2012-01-23       Impact factor: 3.481

9.  Application of volumetric modulated arc therapy (VMAT) in a dual-vendor environment.

Authors:  Barbara Dobler; Karin Weidner; Oliver Koelbl
Journal:  Radiat Oncol       Date:  2010-10-25       Impact factor: 3.481

10.  Evaluation of volumetric modulated arc therapy (VMAT) with Oncentra MasterPlan® for the treatment of head and neck cancer.

Authors:  Judith Alvarez-Moret; Fabian Pohl; Oliver Koelbl; Barbara Dobler
Journal:  Radiat Oncol       Date:  2010-11-22       Impact factor: 3.481

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