Literature DB >> 20186515

Increased occurrence of cardiovascular events and comorbidities in a general rheumatology cohort.

A Mohammad1, K Hartery, U Bond, M Phelan.   

Abstract

BACKGROUND: To identify cardiovascular and other comorbidities in a general rheumatology cohort.
METHODS: Interviews/retrospective chart audits were conducted on 1,000 patients attending rheumatology outpatient clinics of a university teaching hospital. Comorbidities were classified using the Charlson comorbidity index (Ambrose et al. in Ir J Med Sci 178(1):53-55, 2009).
RESULTS: Mean age 58 +/- 15.3 years, mean BMI 26. Of the patients, 400 (40%) were diagnosed with dyslipidemia and hypertension (p = 0.002), 160 (16%) with obesity and 80 (8%) with hypothyroidism. Overall 160 (16%) patients were diagnosed with coronary heart disease (CHD). Of these, 120 (75%) had RA (p = 0.001), 100 (63%) were male, mean age 60 +/- 15.8 years, 120 (75%) had dyslipidemia and BMI > 30 (p = 0.002), 112 (70%) were smokers (p = 0.002), 40 (25%) were diagnosed with diabetes mellitus and 20 (12%) with hypothyroidism.
CONCLUSIONS: The increased prevalence of these comorbidities may serve as a reminder to the rheumatologists that many of their patients will have coexistent disease of which they need to be aware to properly plan their management.

Entities:  

Mesh:

Year:  2010        PMID: 20186515     DOI: 10.1007/s11845-010-0475-5

Source DB:  PubMed          Journal:  Ir J Med Sci        ISSN: 0021-1265            Impact factor:   1.568


  26 in total

Review 1.  Patient questionnaires and formal education as more significant prognostic markers than radiographs or laboratory tests for rheumatoid arthritis mortality--limitations of a biomedical model to predict long-term outcomes.

Authors:  Theodore Pincus
Journal:  Bull NYU Hosp Jt Dis       Date:  2007

2.  A new method of classifying prognostic comorbidity in longitudinal studies: development and validation.

Authors:  M E Charlson; P Pompei; K L Ales; C R MacKenzie
Journal:  J Chronic Dis       Date:  1987

3.  Contribution of congestive heart failure and ischemic heart disease to excess mortality in rheumatoid arthritis.

Authors:  Paulo J Nicola; Cynthia S Crowson; Hilal Maradit-Kremers; Karla V Ballman; Véronique L Roger; Steven J Jacobsen; Sherine E Gabriel
Journal:  Arthritis Rheum       Date:  2006-01

4.  Observed and expected frequency of comorbid chronic diseases in rheumatic patients.

Authors:  E Loza; J A Jover; L Rodriguez-Rodriguez; L Carmona
Journal:  Ann Rheum Dis       Date:  2007-11-02       Impact factor: 19.103

5.  Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation.

Authors:  K G Alberti; P Z Zimmet
Journal:  Diabet Med       Date:  1998-07       Impact factor: 4.359

Review 6.  Rheumatoid arthritis and cardiovascular disease.

Authors:  Saurabh S Dhawan; Arshed A Quyyumi
Journal:  Curr Atheroscler Rep       Date:  2008-04       Impact factor: 5.113

Review 7.  Clinical utility and cost-effectiveness of sensitive thyrotropin assays in ambulatory and hospitalized patients.

Authors:  C A Spencer
Journal:  Mayo Clin Proc       Date:  1988-12       Impact factor: 7.616

8.  Influence of nonclassical cardiovascular risk factors on the accuracy of predicting subclinical atherosclerosis in rheumatoid arthritis.

Authors:  Patrick H Dessein; Gavin R Norton; Angela J Woodiwiss; Barry I Joffe; Fred Wolfe
Journal:  J Rheumatol       Date:  2007-04-15       Impact factor: 4.666

Review 9.  Executive summary of the clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults.

Authors: 
Journal:  Arch Intern Med       Date:  1998-09-28

10.  Limiting cardiovascular risk in Irish rheumatoid arthritis patients.

Authors:  N L Ambrose; P O'Connell; G Kearns
Journal:  Ir J Med Sci       Date:  2008-11-13       Impact factor: 1.568

View more
  2 in total

Review 1.  The impact of traditional cardiovascular risk factors on cardiovascular outcomes in patients with rheumatoid arthritis: a systematic review and meta-analysis.

Authors:  Leena R Baghdadi; Richard J Woodman; E Michael Shanahan; Arduino A Mangoni
Journal:  PLoS One       Date:  2015-02-17       Impact factor: 3.240

2.  Association of the Charlson comorbidity index with renal outcome and all-cause mortality in antineutrophil cytoplasmatic antibody-associated vasculitis.

Authors:  Shachaf Ofer-Shiber; Yair Molad
Journal:  Medicine (Baltimore)       Date:  2014-11       Impact factor: 1.889

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.