Literature DB >> 20181196

Unexpected aflatoxin exposure in a woman in northern Italy: a case report.

Riccardo Perduri1, Stefania Gobba.   

Abstract

INTRODUCTION: In well-developed countries scant attention is currently devoted to the risk of unknown exposure to aflatoxins, highly toxic and carcinogenic compounds. Nevertheless, unexpected ingestion of foods contaminated by these toxins can occasionally occur virtually worldwide. CASE
PRESENTATION: A 38-year-old woman living in Northern Italy developed unexplained abdominal symptoms after ingestion of aflatoxin-contaminated meat. The possible relation between symptoms and aflatoxins ingestion, the potential risk of hepatocellular carcinoma and the medical management of the case are discussed.
CONCLUSION: In well-developed countries aflatoxins exposure should be considered in case of unexplained abdominal symptoms. Cancer risk cannot be assessed, nevertheless individual counselling and periodical medical examinations are recommended.

Entities:  

Year:  2009        PMID: 20181196      PMCID: PMC2827137          DOI: 10.1186/1757-1626-0002-0000007736

Source DB:  PubMed          Journal:  Cases J        ISSN: 1757-1626


  12 in total

Review 1.  Role of metabolism and viruses in aflatoxin-induced liver cancer.

Authors:  John D Groopman; Thomas W Kensler
Journal:  Toxicol Appl Pharmacol       Date:  2005-08-07       Impact factor: 4.219

Review 2.  [The significance of mycotoxin assimilation for meat animals].

Authors:  J Fink-Gremmels
Journal:  Dtsch Tierarztl Wochenschr       Date:  1989 Jul-Aug

Review 3.  Toxic effects of mycotoxins in humans.

Authors:  M Peraica; B Radić; A Lucić; M Pavlović
Journal:  Bull World Health Organ       Date:  1999       Impact factor: 9.408

4.  Apiaceous vegetable constituents inhibit human cytochrome P-450 1A2 (hCYP1A2) activity and hCYP1A2-mediated mutagenicity of aflatoxin B1.

Authors:  Sabrina Peterson; Johanna W Lampe; Theo K Bammler; Kerstin Gross-Steinmeyer; David L Eaton
Journal:  Food Chem Toxicol       Date:  2006-04-27       Impact factor: 6.023

Review 5.  Chemoprevention of hepatocellular carcinoma in aflatoxin endemic areas.

Authors:  Thomas W Kensler; Patricia A Egner; Jin-Bing Wang; Yuan-Rong Zhu; Bao-Chu Zhang; Pei-Xin Lu; Jian-Guo Chen; Geng-Sun Qian; Shuang-Yuan Kuang; Peta E Jackson; Stephen J Gange; Lisa P Jacobson; Alvaro Muñoz; John D Groopman
Journal:  Gastroenterology       Date:  2004-11       Impact factor: 22.682

6.  Mutational hotspot in the p53 gene in human hepatocellular carcinomas.

Authors:  I C Hsu; R A Metcalf; T Sun; J A Welsh; N J Wang; C C Harris
Journal:  Nature       Date:  1991-04-04       Impact factor: 49.962

7.  Acute effects of aflatoxins on guinea pig isolated ileum.

Authors:  A Luzi; M F Cometa; M Palmery
Journal:  Toxicol In Vitro       Date:  2002-10       Impact factor: 3.500

Review 8.  Mycotoxins.

Authors:  J W Bennett; M Klich
Journal:  Clin Microbiol Rev       Date:  2003-07       Impact factor: 26.132

9.  Epidemic of toxic hepatitis in India of possible mycotoxic origin.

Authors:  H D Tandon; B N Tandon; V Ramalingaswami
Journal:  Arch Pathol Lab Med       Date:  1978-07       Impact factor: 5.534

10.  Investigation of acute effects of aflatoxin on rat proximal and distal colon spontaneous contractions.

Authors:  Nevcihan Gursoy; Nedim Durmus; Ihsan Bagcivan; Bulent Sarac; Ahmet Parlak; Sahin Yildirim; Tijen Kaya
Journal:  Food Chem Toxicol       Date:  2008-06-02       Impact factor: 6.023

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