Literature DB >> 2018092

Syntactic delay and pragmatic deviance in the language of fragile X males.

V Sudhalter1, H S Scarborough, I L Cohen.   

Abstract

The expressive language of 19 fragile X [fra(X)] males with chronological ages between 5 and 36 years and Vineland Adaptive Behavior Scores between 21 and 79 was examined for syntactic as well as pragmatic proficiency. The production of deviant repetitive language was observed with this group, corroborating the results of an earlier study with a smaller sample of fra(X) males. In contrast, when 2 syntax scores, mean length of utterance (MLU), and Index of Productive Syntax (IPSyn) were derived from naturalistic language observations, the relation of complexity to length was observed to be very similar to the known relationship of these 2 facets of syntactic ability in normal preschoolers. These results, and the absence of correlations between syntactic scores and proportions of deviant repetitive language are consistent with the notion that the syntactic development of fra(X) males is typically delayed rather than deviant. For effective assessment and remediation of communicative problems associated with the syndrome to be developed, it is argued, language must be considered as a combination of competencies rather than as a unitary skill.

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Year:  1991        PMID: 2018092     DOI: 10.1002/ajmg.1320380270

Source DB:  PubMed          Journal:  Am J Med Genet        ISSN: 0148-7299


  16 in total

1.  Expressive language profiles of verbally expressive adolescents and young adults with Down syndrome or fragile X syndrome.

Authors:  Lizbeth H Finestack; Leonard Abbeduto
Journal:  J Speech Lang Hear Res       Date:  2010-07-19       Impact factor: 2.297

2.  Longitudinal profiles of expressive vocabulary, syntax and pragmatic language in boys with fragile X syndrome or Down syndrome.

Authors:  Gary E Martin; Molly Losh; Bruno Estigarribia; John Sideris; Joanne Roberts
Journal:  Int J Lang Commun Disord       Date:  2013-04-19       Impact factor: 3.020

3.  Language Skills of Males with Fragile X Syndrome or Nonsyndromic Autism Spectrum Disorder.

Authors:  Angela John Thurman; Andrea McDuffie; Randi J Hagerman; Cynde K Josol; Leonard Abbeduto
Journal:  J Autism Dev Disord       Date:  2017-03

4.  Cognitive, environmental, and linguistic predictors of syntax in fragile X syndrome and Down syndrome.

Authors:  Bruno Estigarribia; Gary E Martin; Joanne E Roberts
Journal:  J Speech Lang Hear Res       Date:  2012-04-03       Impact factor: 2.297

5.  Growth of Expressive Syntax in Children With Fragile X Syndrome.

Authors:  Rouzana Komesidou; Nancy C Brady; Kandace Fleming; Amy Esplund; Steven F Warren
Journal:  J Speech Lang Hear Res       Date:  2017-02-01       Impact factor: 2.297

6.  Language Development in Individuals with Fragile X Syndrome.

Authors:  Lizbeth H Finestack; Erica K Richmond; Leonard Abbeduto
Journal:  Top Lang Disord       Date:  2009-04

7.  Expressive language in male adolescents with fragile X syndrome with and without comorbid autism.

Authors:  S T Kover; L Abbeduto
Journal:  J Intellect Disabil Res       Date:  2010-02-08

8.  The language phenotype of children and adolescents with Noonan syndrome.

Authors:  Elizabeth I Pierpont; Susan Ellis Weismer; Amy E Roberts; Erica Tworog-Dube; Mary Ella Pierpont; Nancy J Mendelsohn; Mark S Seidenberg
Journal:  J Speech Lang Hear Res       Date:  2010-06-11       Impact factor: 2.297

9.  Perseveration in the connected speech of boys with Fragile X syndrome with and without autism spectrum disorder.

Authors:  Gary E Martin; Joanne E Roberts; Nancy Helm-Estabrooks; John Sideris; Jacqueline Vanderbilt; Lauren Moskowitz
Journal:  Am J Intellect Dev Disabil       Date:  2012-09

Review 10.  Neuropsychiatric symptoms of fragile X syndrome: pathophysiology and pharmacotherapy.

Authors:  John A Tsiouris; W Ted Brown
Journal:  CNS Drugs       Date:  2004       Impact factor: 5.749

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