Literature DB >> 20176049

Molecular therapeutic approaches to melanoma.

Zhenyu Ji1, Keith T Flaherty, Hensin Tsao.   

Abstract

Metastatic melanoma is a highly lethal cancer that has historically been refractory to all tested pharmacological agents. An understanding of the mechanisms responsible for its oncogenesis is critical for developing successful therapies. An enormous amount of data generated over the last few decades have revealed important biological insights into melanoma initiation, progression and maintenance, which bring new directions and approaches to treatment of this devastating skin cancer. Copyright 2010 Elsevier Ltd. All rights reserved.

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Year:  2010        PMID: 20176049     DOI: 10.1016/j.mam.2010.02.004

Source DB:  PubMed          Journal:  Mol Aspects Med        ISSN: 0098-2997


  7 in total

1.  Synthesis and Biological Evaluation of New Quinoxaline Derivatives of ICF01012 as Melanoma-Targeting Probes.

Authors:  Radhia El Aissi; Jianrong Liu; Sophie Besse; Damien Canitrot; Olivier Chavignon; Jean-Michel Chezal; Elisabeth Miot-Noirault; Emmanuel Moreau
Journal:  ACS Med Chem Lett       Date:  2014-02-20       Impact factor: 4.345

Review 2.  Targeting the RAS pathway in melanoma.

Authors:  Zhenyu Ji; Keith T Flaherty; Hensin Tsao
Journal:  Trends Mol Med       Date:  2011-09-30       Impact factor: 11.951

Review 3.  Molecular testing in melanoma.

Authors:  Melissa Ann Wilson; Katherine L Nathanson
Journal:  Cancer J       Date:  2012 Mar-Apr       Impact factor: 3.360

Review 4.  Clinical Pharmacokinetic and Pharmacodynamic Considerations in the (Modern) Treatment of Melanoma.

Authors:  Hannah Yejin Kim; Parth J Upadhyay; Alia Fahmy; Xiaoman Liu; Janna K Duong; Alan V Boddy
Journal:  Clin Pharmacokinet       Date:  2019-08       Impact factor: 6.447

5.  Protective Effect of Genistein on Cyclin D1 Expression in Malignant Ocular Melanoma Cells.

Authors:  Yasmin Sani Aprilliantina; Hera Dwi Novita; Elfina G Sadono; Rosy Aldina
Journal:  Med Arch       Date:  2021-06

6.  Spirooxindole derivative SOID-8 induces apoptosis associated with inhibition of JAK2/STAT3 signaling in melanoma cells.

Authors:  Yan Tian; Sangkil Nam; Lucy Liu; Fumiko Yakushijin; Kenichi Yakushijin; Ralf Buettner; Wei Liang; Fan Yang; Yuelong Ma; David Horne; Richard Jove
Journal:  PLoS One       Date:  2012-11-16       Impact factor: 3.240

7.  Phase II study of the farnesyltransferase inhibitor R115777 in advanced melanoma (CALGB 500104).

Authors:  Thomas F Gajewski; April K S Salama; Donna Niedzwiecki; Jeffrey Johnson; Gerald Linette; Cynthia Bucher; Michelle A Blaskovich; Said M Sebti; Frank Haluska
Journal:  J Transl Med       Date:  2012-12-10       Impact factor: 5.531

  7 in total

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