Literature DB >> 20173471

Sacral nerve stimulation is a valid approach in fecal incontinence due to sphincter lesions when compared to sphincter repair.

Carlo Ratto1, Francesco Litta, Angelo Parello, Lorenza Donisi, Giovanni Battista Doglietto.   

Abstract

PURPOSE: Anal sphincter lesions represent the major cause of fecal incontinence, particularly in women. Sphincteroplasty with overlap is the traditional treatment, but a significant reduction in benefits within 5 years of surgery has been reported. More recently, sacral nerve stimulation has been suggested following sphincteroplasty or as primary treatment.
METHODS: Overall, 24 women with fecal incontinence in the presence of anal sphincter lesions underwent sphincteroplasty (14 patients, mean age 47.6 +/- 15.6 years, range 26-70) or definitive implant of sacral nerve stimulation (10 patients, mean age 60.7 +/- 17.6 years, range 26-73), using identical selection criteria. At baseline, patients were studied with clinical evaluation, 3-dimensional endoanal ultrasound, and anorectal manometry (ARM), repeated at follow-up (median 60.0 months, range 6-96 in sphincteroplasty group; median 33.0 months, range 6-84 in sacral nerve stimulation group).
RESULTS: At baseline, both groups presented similar characteristics. Two sphincteroplasty patients (14.3%) experienced relapse of fecal incontinence at 6 and 19 months after treatment, whereas good to excellent continence was observed in all of the sacral nerve stimulation patients. Compared to baseline, both groups showed a significant improvement in clinical parameters, and ARM data remained unchanged. In 12 of 14 sphincteroplasty patients, the repaired sphincter at endoanal ultrasound was found to overlap. At follow-up, comparison between sphincteroplasty and sacral nerve stimulation showed no significant differences in clinical and ARM parameters, if related to lesion of internal, external, or both sphincters.
CONCLUSIONS: These data appear to confirm that sacral nerve stimulation could represent a valid alternative in the treatment of fecal incontinence patients presenting with sphincter lesion that was not preceded by sphincteroplasty.

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Year:  2010        PMID: 20173471     DOI: 10.1007/DCR.0b013e3181c7642c

Source DB:  PubMed          Journal:  Dis Colon Rectum        ISSN: 0012-3706            Impact factor:   4.585


  19 in total

1.  Defecation: Sacral nerve stimulation therapy for defecatory disorders.

Authors:  Klaus E Matzel
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2010-07       Impact factor: 46.802

2.  Sphincteroplasty for fecal incontinence in the era of sacral nerve modulation.

Authors:  Donato F Altomare; Michele De Fazio; Ramona Tiziana Giuliani; Giorgio Catalano; Filippa Cuccia
Journal:  World J Gastroenterol       Date:  2010-11-14       Impact factor: 5.742

Review 3.  Neuromodulation for fecal incontinence: an effective surgical intervention.

Authors:  Giuseppe Chiarioni; Olafur S Palsson; Corrado R Asteria; William E Whitehead
Journal:  World J Gastroenterol       Date:  2013-11-07       Impact factor: 5.742

Review 4.  Current management of fecal incontinence: choosing amongst treatment options to optimize outcomes.

Authors:  Julie Ann M Van Koughnett; Steven D Wexner
Journal:  World J Gastroenterol       Date:  2013-12-28       Impact factor: 5.742

Review 5.  Impact of fecal incontinence and its treatment on quality of life in women.

Authors:  Isuzu Meyer; Holly E Richter
Journal:  Womens Health (Lond)       Date:  2015-03

6.  Long-term outcome after overlapping anterior anal sphincter repair for fecal incontinence.

Authors:  Gery Lamblin; Paule Bouvier; Henri Damon; Philippe Chabert; Stephanie Moret; Gautier Chene; Georges Mellier
Journal:  Int J Colorectal Dis       Date:  2014-09-04       Impact factor: 2.571

7.  Is sacral neuromodulation here to stay? Clinical outcomes of a new treatment for fecal incontinence.

Authors:  Bobby L Johnson; Adam Abodeely; Martha A Ferguson; Bradley R Davis; Janice F Rafferty; Ian M Paquette
Journal:  J Gastrointest Surg       Date:  2014-08-13       Impact factor: 3.452

8.  Seven-year follow-up after anterior sphincter reconstruction for faecal incontinence.

Authors:  Kirsi Lehto; Marja Hyöty; Pekka Collin; Heini Huhtala; Petri Aitola
Journal:  Int J Colorectal Dis       Date:  2013-02-26       Impact factor: 2.571

9.  Sacral nerve stimulation for fecal incontinence improves symptoms, quality of life and patients' satisfaction: results of a monocentric series of 119 patients.

Authors:  Henri Damon; Xavier Barth; Sabine Roman; François Mion
Journal:  Int J Colorectal Dis       Date:  2012-08-12       Impact factor: 2.571

10.  Tools for fecal incontinence assessment: lessons for inflammatory bowel disease trials based on a systematic review.

Authors:  Ferdinando D'Amico; Steven D Wexner; Carolynne J Vaizey; Célia Gouynou; Silvio Danese; Laurent Peyrin-Biroulet
Journal:  United European Gastroenterol J       Date:  2020-07-17       Impact factor: 4.623

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