| Literature DB >> 20171514 |
Charles Mayo1, Mary K Martel, Lawrence B Marks, John Flickinger, Jiho Nam, John Kirkpatrick.
Abstract
Publications relating radiation toxicity of the optic nerves and chiasm to quantitative dose and dose-volume measures were reviewed. Few studies have adequate data for dose-volume outcome modeling. The risk of toxicity increased markedly at doses >60 Gy at approximately 1.8 Gy/fraction and at >12 Gy for single-fraction radiosurgery. The evidence is strong that radiation tolerance is increased with a reduction in the dose per fraction. Models of threshold tolerance were examined. Copyright 2010 Elsevier Inc. All rights reserved.Entities:
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Year: 2010 PMID: 20171514 DOI: 10.1016/j.ijrobp.2009.07.1753
Source DB: PubMed Journal: Int J Radiat Oncol Biol Phys ISSN: 0360-3016 Impact factor: 7.038