| Literature DB >> 20170905 |
Zaihong Zhang1, Chengli Zong, Gaopeng Song, Guokai Lv, Yuexing Chun, Peng Wang, Ning Ding, Yingxia Li.
Abstract
The first total synthesis of caminoside B, a novel marine antimicrobial glycolipid isolated from the marine sponge Caminus sphaeroconia, was developed. This marine small molecule inhibitor (IC(50)=20 microM) targeting type III secretory pathway of bacterial pathogenesis was assembled in good yield via a '2+2+1' strategy based on stereocontrolled construction of the four glycosidic linkages. Copyright (c) 2010 Elsevier Ltd. All rights reserved.Entities:
Mesh：
Substances：
Year: 2010 PMID： 20170905 DOI： 10.1016/j.carres.2010.01.015
Source DB: PubMed Journal: Carbohydr Res ISSN： 0008-6215 Impact factor: 2.104