Literature DB >> 2016730

1-(carboxybenzyl)imidazole-5-acrylic acids: potent and selective angiotensin II receptor antagonists.

J Weinstock1, R M Keenan, J Samanen, J Hempel, J A Finkelstein, R G Franz, D E Gaitanopoulos, G R Girard, J G Gleason, D T Hill.   

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Year:  1991        PMID： 2016730     DOI： 10.1021/jm00108a043

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  9 in total

1.  Inhibition of angiotensin II-induced inositol phosphate production by triacid nonpeptide antagonists in CHO cells expressing human AT1 receptors.

Authors:  P M Vanderheyden; I Verheijen; F L Fierens; J P DeBacker; G Vauquelin
Journal:  Pharm Res       Date:  2000-12       Impact factor: 4.200

2.  Derivation of a 3D pharmacophore model for the angiotensin-II site one receptor.

Authors:  K Prendergast; K Adams; W J Greenlee; R B Nachbar; A A Patchett; D J Underwood
Journal:  J Comput Aided Mol Des       Date:  1994-10       Impact factor: 3.686

3.  Antihypertensive activity of the non-peptide angiotensin II receptor antagonist, SK&F 108566, in rats and dogs.

Authors:  D P Brooks; T A Fredrickson; J Weinstock; R R Ruffolo; R M Edwards; M Gellai
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1992-06       Impact factor: 3.000

4.  Methyl 2,5-dichloro-benzoate.

Authors:  Tariq Mahmood Babar; Ghulam Qadeer; Nasim Hasan Rama; Ales Ruzicka; Zdenka Padelkova
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2008-09-20

5.  Differentiation between binding sites for angiotensin II and nonpeptide antagonists on the angiotensin II type 1 receptors.

Authors:  H T Schambye; S A Hjorth; D J Bergsma; G Sathe; T W Schwartz
Journal:  Proc Natl Acad Sci U S A       Date:  1994-07-19       Impact factor: 11.205

6.  Human AT1 receptor is a single copy gene: characterization in a stable cell line.

Authors:  N Aiyar; E Baker; H L Wu; P Nambi; R M Edwards; J J Trill; C Ellis; D J Bergsma
Journal:  Mol Cell Biochem       Date:  1994-02-09       Impact factor: 3.396

7.  A pharmacodynamic study of SR 47436, a selective AT1 receptor antagonist, on blood pressure in conscious cynomolgus monkeys.

Authors:  A Roccon; D Marchionni; F Donat; D Segondy; C Cazaubon; D Nisato
Journal:  Br J Pharmacol       Date:  1994-01       Impact factor: 8.739

8.  Pharmacological profile of valsartan: a potent, orally active, nonpeptide antagonist of the angiotensin II AT1-receptor subtype.

Authors:  L Criscione; M de Gasparo; P Bühlmayer; S Whitebread; H P Ramjoué; J Wood
Journal:  Br J Pharmacol       Date:  1993-10       Impact factor: 8.739

Review 9.  Rational Design and Synthesis of AT1R Antagonists.

Authors:  Nikitas Georgiou; Vasileios K Gkalpinos; Spyridon D Katsakos; Stamatia Vassiliou; Andreas G Tzakos; Thomas Mavromoustakos
Journal:  Molecules       Date:  2021-05-14       Impact factor: 4.411
  9 in total

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