Literature DB >> 20161205

Design, fabrication and demonstration of a magnetophoresis chamber with 25 output fractions.

Chris Carr1, Michelle Espy, Pulak Nath, Sara L Martin, Michael D Ward, John Martin.   

Abstract

Our goal is to develop an instrument for parallel and multiplexed bioassay using magnetic labels. Toward this end we are developing a multi-outlet magnetophoresis instrument incorporating a fluidic flow chamber placed inside a magnetic field gradient. Magnetic microparticles are sorted by their magnetic moment for eventual use as biological labels based on magnetic signature.In this paper we concentrate on developments in our flow chamber fabrication methods that have allowed us to scale the number of sorting channels from 8 to 25. We present data for instrument performance and reproducibility of sorting.

Entities:  

Year:  2009        PMID: 20161205      PMCID: PMC2713114          DOI: 10.1016/j.jmmm.2009.02.064

Source DB:  PubMed          Journal:  J Magn Magn Mater        ISSN: 0304-8853            Impact factor:   2.993


  8 in total

Review 1.  Advances in cell separation: recent developments in counterflow centrifugal elutriation and continuous flow cell separation.

Authors:  J Bauer
Journal:  J Chromatogr B Biomed Sci Appl       Date:  1999-02-05

2.  On-chip free-flow magnetophoresis: continuous flow separation of magnetic particles and agglomerates.

Authors:  Nicole Pamme; Andreas Manz
Journal:  Anal Chem       Date:  2004-12-15       Impact factor: 6.986

3.  Capillary magnetic field flow fractionation and analysis of magnetic nanoparticles.

Authors:  Andrew H Latham; Rafael S Freitas; Peter Schiffer; Mary Elizabeth Williams
Journal:  Anal Chem       Date:  2005-08-01       Impact factor: 6.986

4.  Continuous flow magnetic cell fractionation based on antigen expression level.

Authors:  Thomas Schneider; Lee R Moore; Ying Jing; Seungjoo Haam; P Stephen Williams; Aaron J Fleischman; Shuvo Roy; Jeffrey J Chalmers; Maciej Zborowski
Journal:  J Biochem Biophys Methods       Date:  2006-03-29

5.  An instrument for sorting of magnetic microparticles in a magnetic field gradient.

Authors:  Michelle A Espy; Henrik Sandin; Chris Carr; Christina J Hanson; Michael D Ward; Robert H Kraus
Journal:  Cytometry A       Date:  2006-11-01       Impact factor: 4.355

6.  Continuous, flow-through immunomagnetic cell sorting in a quadrupole field.

Authors:  L Sun; M Zborowski; L R Moore; J J Chalmers
Journal:  Cytometry       Date:  1998-12-01

Review 7.  Immunomagnetic cell sorting--pushing the limits.

Authors:  A Thiel; A Scheffold; A Radbruch
Journal:  Immunotechnology       Date:  1998-10

8.  Lymphocyte fractionation using immunomagnetic colloid and a dipole magnet flow cell sorter.

Authors:  L R Moore; M Zborowski; L Sun; J J Chalmers
Journal:  J Biochem Biophys Methods       Date:  1998-09-24
  8 in total
  2 in total

Review 1.  Microfluidic cell sorting: a review of the advances in the separation of cells from debulking to rare cell isolation.

Authors:  C Wyatt Shields; Catherine D Reyes; Gabriel P López
Journal:  Lab Chip       Date:  2015-03-07       Impact factor: 6.799

2.  High-throughput chemical and chemoenzymatic approaches to saccharide-coated magnetic nanoparticles for MRI.

Authors:  Thomas W Fallows; Andrew J McGrath; Joana Silva; Simon G McAdams; Andrea Marchesi; Floriana Tuna; Sabine L Flitsch; Richard D Tilley; Simon J Webb
Journal:  Nanoscale Adv       Date:  2019-07-29
  2 in total

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