Literature DB >> 20161153

Characterization of magnetite nanoparticles for SQUID-relaxometry and magnetic needle biopsy.

Natalie L Adolphi1, Dale L Huber, Jason E Jaetao, Howard C Bryant, Debbie M Lovato, Danielle L Fegan, Eugene L Venturini, Todd C Monson, Trace E Tessier, Helen J Hathaway, Christian Bergemann, Richard S Larson, Edward R Flynn.   

Abstract

Magnetite nanoparticles (Chemicell SiMAG-TCL) were characterized by SQUID-relaxometry, susceptometry, and TEM. The magnetization detected by SQUID-relaxometry was 0.33% of that detected by susceptometry, indicating that the sensitivity of SQUID-relaxometry could be significantly increased through improved control of nanoparticle size. The relaxometry data were analyzed by the moment superposition model (MSM) to determine the distribution of nanoparticle moments. Analysis of the binding of CD34-conjugated nanoparticles to U937 leukemia cells revealed 60,000 nanoparticles per cell, which were collected from whole blood using a prototype magnetic biopsy needle, with a capture efficiency of >65% from a 750 µl sample volume in 1 minute.

Entities:  

Year:  2009        PMID： 20161153      PMCID： PMC2734090          DOI： 10.1016/j.jmmm.2009.02.067

Source DB:  PubMed          Journal:  J Magn Magn Mater        ISSN： 0304-8853            Impact factor:   2.993


  5 in total

1.  Ultrasensitive magnetic biosensor for homogeneous immunoassay.

Authors:  Y R Chemla; H L Grossman; Y Poon; R McDermott; R Stevens; M D Alper; J Clarke
Journal:  Proc Natl Acad Sci U S A       Date:  2000-12-19       Impact factor: 11.205

Review 2.  Clinical and biological significance of CD34 expression in acute leukemia.

Authors:  G Basso; F Lanza; A Orfao; S Moretti; G Castoldi
Journal:  J Biol Regul Homeost Agents       Date:  2001 Jan-Mar       Impact factor: 1.711

3.  A biomagnetic system for in vivo cancer imaging.

Authors:  E R Flynn; H C Bryant
Journal:  Phys Med Biol       Date:  2005-03-02       Impact factor: 3.609

4.  Magnetic needles and superparamagnetic cells.

Authors:  H C Bryant; D A Sergatskov; Debbie Lovato; Natalie L Adolphi; Richard S Larson; Edward R Flynn
Journal:  Phys Med Biol       Date:  2007-06-08       Impact factor: 3.609

5.  Determination of energy barrier distributions of magnetic nanoparticles by temperature dependent magnetorelaxometry.

Authors:  E Romanus; D V Berkov; S Prass; C Groß; W Weitschies; P Weber
Journal:  Nanotechnology       Date:  2003-10-17       Impact factor: 3.874
  5 in total
  12 in total

1.  Magnetic Properties of Nanoparticles Useful for SQUID Relaxometry in Biomedical Applications.

Authors:  H C Bryant; Natalie L Adolphi; Dale L Huber; Danielle L Fegan; Todd C Monson; Trace E Tessier; Edward R Flynn
Journal:  J Magn Magn Mater       Date:  2011-03-01       Impact factor: 2.993

2.  Magnetic Relaxometry with an Atomic Magnetometer and SQUID Sensors on Targeted Cancer Cells.

Authors:  Cort Johnson; Natalie L Adolphi; Kimberly L Butler; Lovato Debbie M; Richard Larson; Peter D D Schwindt; Edward R Flynn
Journal:  J Magn Magn Mater       Date:  2012-08-01       Impact factor: 2.993

3.  Screening for ovarian cancer: imaging challenges and opportunities for improvement.

Authors:  K B Mathieu; D G Bedi; S L Thrower; A Qayyum; R C Bast
Journal:  Ultrasound Obstet Gynecol       Date:  2018-03       Impact factor: 7.299

4.  Imaging of Her2-targeted magnetic nanoparticles for breast cancer detection: comparison of SQUID-detected magnetic relaxometry and MRI.

Authors:  Natalie L Adolphi; Kimberly S Butler; Debbie M Lovato; T E Tessier; Jason E Trujillo; Helen J Hathaway; Danielle L Fegan; Todd C Monson; Tyler E Stevens; Dale L Huber; Jaivijay Ramu; Michelle L Milne; Stephen A Altobelli; Howard C Bryant; Richard S Larson; Edward R Flynn
Journal:  Contrast Media Mol Imaging       Date:  2012 May-Jun       Impact factor: 3.161

5.  Characterization of single-core magnetite nanoparticles for magnetic imaging by SQUID relaxometry.

Authors:  Natalie L Adolphi; Dale L Huber; Howard C Bryant; Todd C Monson; Danielle L Fegan; Jitkang Lim; Jason E Trujillo; Trace E Tessier; Debbie M Lovato; Kimberly S Butler; Paula P Provencio; Helen J Hathaway; Sara A Majetich; Richard S Larson; Edward R Flynn
Journal:  Phys Med Biol       Date:  2010-09-21       Impact factor: 3.609

6.  Modeling the efficiency of a magnetic needle for collecting magnetic cells.

Authors:  Kimberly S Butler; Natalie L Adolphi; H C Bryant; Debbie M Lovato; Richard S Larson; Edward R Flynn
Journal:  Phys Med Biol       Date:  2014-05-29       Impact factor: 3.609

7.  Enhanced leukemia cell detection using a novel magnetic needle and nanoparticles.

Authors:  Jason E Jaetao; Kimberly S Butler; Natalie L Adolphi; Debbie M Lovato; Howard C Bryant; Ian Rabinowitz; Stuart S Winter; Trace E Tessier; Helen J Hathaway; Christian Bergemann; Edward R Flynn; Richard S Larson
Journal:  Cancer Res       Date:  2009-10-06       Impact factor: 12.701

8.  Detection of breast cancer cells using targeted magnetic nanoparticles and ultra-sensitive magnetic field sensors.

Authors:  Helen J Hathaway; Kimberly S Butler; Natalie L Adolphi; Debbie M Lovato; Robert Belfon; Danielle Fegan; Todd C Monson; Jason E Trujillo; Trace E Tessier; Howard C Bryant; Dale L Huber; Richard S Larson; Edward R Flynn
Journal:  Breast Cancer Res       Date:  2011-11-03       Impact factor: 6.466

Review 9.  Nanopharmaceuticals (part 2): products in the pipeline.

Authors:  Volkmar Weissig; Diana Guzman-Villanueva
Journal:  Int J Nanomedicine       Date:  2015-02-11

10.  Giant Magnetoresistive Biosensors for Time-Domain Magnetorelaxometry: A Theoretical Investigation and Progress Toward an Immunoassay.

Authors:  Chih-Cheng Huang; Xiahan Zhou; Drew A Hall
Journal:  Sci Rep       Date:  2017-04-04       Impact factor: 4.379
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