Literature DB >> 20160877

DESIGN OF LIPOSOMES CONTAINING PHOTOPOLYMERIZABLE PHOSPHOLIPIDS FOR TRIGGERED RELEASE OF CONTENTS.

Amichai Yavlovich1, Alok Singh, Sergey Tarasov, Jacek Capala, Robert Blumenthal, Anu Puri.   

Abstract

We describe a novel class of light-triggerable liposomes prepared from a photo-polymerizable phospholipid DC(8,9)PC (1,2- bis (tricosa-10,12-diynoyl)-sn-glycero-3-phosphocholine) and DPPC (1,2-Dipalmitoyl-sn-Glycero-3-Phosphocholine). Exposure to UV (254 nm) radiation for 0-45 minutes at 25 degrees C resulted in photo-polymerization of DC(8,9)PC in these liposomes and the release of an encapsulated fluorescent dye (calcein). Kinetics and extents of calcein release correlated with mol% of DC(8,9)PC in the liposomes. Photopolymerization and calcein release occurred only from DPPC/DC(8,9)PC but not from Egg PC/DC(8,9)PC liposomes. Our data indicate that phase separation and packing of polymerizable lipids in the liposome bilayer are major determinants of photo-activation and triggered contents release.

Entities:  

Year:  2009        PMID： 20160877      PMCID： PMC2772073          DOI： 10.1007/s10973-009-0228-8

Source DB:  PubMed          Journal:  J Therm Anal Calorim        ISSN： 0368-4466            Impact factor:   4.626


  18 in total

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Journal:  Biochemistry       Date:  1983-06-21       Impact factor: 3.162

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Journal:  Chem Phys Lipids       Date:  1991-10       Impact factor: 3.329

Review 6.  Polyethylene glycol-coated (pegylated) liposomal doxorubicin. Rationale for use in solid tumours.

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Journal:  Drugs       Date:  1997       Impact factor: 9.546

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Journal:  Chem Phys Lipids       Date:  1983-11       Impact factor: 3.329

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  35 in total

Review 1.  Stimuli-responsive liposomes for drug delivery.

Authors:  Y Lee; D H Thompson
Journal:  Wiley Interdiscip Rev Nanomed Nanobiotechnol       Date:  2017-02-15

Review 2.  Polymeric lipid assemblies as novel theranostic tools.

Authors:  Anu Puri; Robert Blumenthal
Journal:  Acc Chem Res       Date:  2011-09-15       Impact factor: 22.384

3.  Material properties of matrix lipids determine the conformation and intermolecular reactivity of diacetylenic phosphatidylcholine in the lipid bilayer.

Authors:  Anu Puri; Hyunbum Jang; Amichai Yavlovich; M Athar Masood; Timothy D Veenstra; Carlos Luna; Helim Aranda-Espinoza; Ruth Nussinov; Robert Blumenthal
Journal:  Langmuir       Date:  2011-11-21       Impact factor: 3.882

4.  Characterization of restricted diffusion in uni- and multi-lamellar vesicles using short distance iMQCs.

Authors:  A M Stokes; J W Wilson; W S Warren
Journal:  J Magn Reson       Date:  2012-08-14       Impact factor: 2.229

5.  Phase segregation of polymerizable lipids to construct filters for separating lipid-membrane-embedded species.

Authors:  Shu-Kai Hu; Ya-Ming Chen; Ling Chao
Journal:  Biomicrofluidics       Date:  2014-09-12       Impact factor: 2.800

Review 6.  Nanomedical engineering: shaping future nanomedicines.

Authors:  Dandan Luo; Kevin A Carter; Jonathan F Lovell
Journal:  Wiley Interdiscip Rev Nanomed Nanobiotechnol       Date:  2014-11-06

Review 7.  Nanoplatforms for Targeted Stimuli-Responsive Drug Delivery: A Review of Platform Materials and Stimuli-Responsive Release and Targeting Mechanisms.

Authors:  Yuzhe Sun; Edward Davis
Journal:  Nanomaterials (Basel)       Date:  2021-03-16       Impact factor: 5.076

Review 8.  Lipid-based drug delivery systems in the treatment of wet age-related macular degeneration.

Authors:  Joanne D Du; Wye-Khay Fong; Suzanne Caliph; Ben J Boyd
Journal:  Drug Deliv Transl Res       Date:  2016-12       Impact factor: 4.617

9.  Maintenance of ischemic β cell viability through delivery of lipids and ATP by targeted liposomes.

Authors:  Nicole Atchison; Garrett Swindlehurst; Klearchos K Papas; Michael Tsapatsis; Efrosini Kokkoli
Journal:  Biomater Sci       Date:  2014-04-01       Impact factor: 6.843

10.  Fibrin-Targeted Polymerized Shell Microbubbles as Potential Theranostic Agents for Surgical Adhesions.

Authors:  Catherine A Gormley; Benjamin J Keenan; Jo Ann Buczek-Thomas; Amanda C S N Pessoa; Jiang Xu; Fabrice Monti; Patrick Tabeling; R Glynn Holt; Jon O Nagy; Joyce Y Wong
Journal:  Langmuir       Date:  2019-02-08       Impact factor: 3.882
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