Literature DB >> 20160841

A Robust QTL Mapping Procedure.

Fei Zou1, Lei Nie, Fred A Wright, Pranab K Sen.   

Abstract

In quantitative-trait linkage studies using experimental crosses, the conventional normal location-shift model or other parameterizations may be unnecessarily restrictive. We generalize the mapping problem to a genuine nonparametric setup and provide a robust estimation procedure for the situation where the underlying phenotype distributions are completely unspecified. Classical Wilcoxon-Mann-Whitney statistics are employed for point and interval estimation of QTL positions and effects.

Entities:  

Year:  2009        PMID: 20160841      PMCID: PMC2632598          DOI: 10.1016/j.jspi.2008.06.009

Source DB:  PubMed          Journal:  J Stat Plan Inference        ISSN: 0378-3758            Impact factor:   1.111


  22 in total

1.  Multipoint analysis using affected sib pairs: incorporating linkage evidence from unlinked regions.

Authors:  K Y Liang; Y F Chiu; T H Beaty; M Wjst
Journal:  Genet Epidemiol       Date:  2001-09       Impact factor: 2.135

Review 2.  The nature and identification of quantitative trait loci: a community's view.

Authors:  Oduola Abiola; Joe M Angel; Philip Avner; Alexander A Bachmanov; John K Belknap; Beth Bennett; Elizabeth P Blankenhorn; David A Blizard; Valerie Bolivar; Gundrun A Brockmann; Kari J Buck; Jean-Francoise Bureau; William L Casley; Elissa J Chesler; James M Cheverud; Gary A Churchill; Melloni Cook; John C Crabbe; Wim E Crusio; Ariel Darvasi; Gerald de Haan; Peter Dermant; R W Doerge; Rosemary W Elliot; Charles R Farber; Lorraine Flaherty; Jonathan Flint; Howard Gershenfeld; John P Gibson; Jing Gu; Weikuan Gu; Heinz Himmelbauer; Robert Hitzemann; Hui-Chen Hsu; Kent Hunter; Fuad F Iraqi; Ritsert C Jansen; Thomas E Johnson; Byron C Jones; Gerd Kempermann; Frank Lammert; Lu Lu; Kenneth F Manly; Douglas B Matthews; Juan F Medrano; Margarete Mehrabian; Guy Mittlemann; Beverly A Mock; Jeffrey S Mogil; Xavier Montagutelli; Grant Morahan; John D Mountz; Hiroki Nagase; Richard S Nowakowski; Bruce F O'Hara; Alexander V Osadchuk; Beverly Paigen; Abraham A Palmer; Jeremy L Peirce; Daniel Pomp; Michael Rosemann; Glenn D Rosen; Leonard C Schalkwyk; Ze'ev Seltzer; Stephen Settle; Kazuhiro Shimomura; Siming Shou; James M Sikela; Linda D Siracusa; Jimmy L Spearow; Cory Teuscher; David W Threadgill; Linda A Toth; Ayo A Toye; Csaba Vadasz; Gary Van Zant; Edward Wakeland; Robert W Williams; Huang-Ge Zhang; Fei Zou
Journal:  Nat Rev Genet       Date:  2003-11       Impact factor: 53.242

3.  Using advanced intercross lines for high-resolution mapping of HDL cholesterol quantitative trait loci.

Authors:  Xiaosong Wang; Isabelle Le Roy; Edwige Nicodeme; Renhua Li; Richard Wagner; Christina Petros; Gary A Churchill; Stephen Harris; Ariel Darvasi; Jorge Kirilovsky; Pierre L Roubertoux; Beverly Paigen
Journal:  Genome Res       Date:  2003-06-12       Impact factor: 9.043

4.  Simultaneous localization of two linked disease susceptibility genes.

Authors:  Joanna M Biernacka; Lei Sun; Shelley B Bull
Journal:  Genet Epidemiol       Date:  2005-01       Impact factor: 2.135

5.  A simple regression method for mapping quantitative trait loci in line crosses using flanking markers.

Authors:  C S Haley; S A Knott
Journal:  Heredity (Edinb)       Date:  1992-10       Impact factor: 3.821

6.  QTL analysis: a simple 'marker-regression' approach.

Authors:  M J Kearsey; V Hyne
Journal:  Theor Appl Genet       Date:  1994-11       Impact factor: 5.699

7.  Statistical methods for mapping quantitative trait loci from a dense set of markers.

Authors:  J Dupuis; D Siegmund
Journal:  Genetics       Date:  1999-01       Impact factor: 4.562

8.  A simple method to calculate resolving power and confidence interval of QTL map location.

Authors:  A Darvasi; M Soller
Journal:  Behav Genet       Date:  1997-03       Impact factor: 2.805

9.  Mapping mendelian factors underlying quantitative traits using RFLP linkage maps.

Authors:  E S Lander; D Botstein
Journal:  Genetics       Date:  1989-01       Impact factor: 4.562

10.  Asymptotic theory for gene mapping.

Authors:  A Kong; F Wright
Journal:  Proc Natl Acad Sci U S A       Date:  1994-10-11       Impact factor: 11.205

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  4 in total

Review 1.  Mapping complex traits as a dynamic system.

Authors:  Lidan Sun; Rongling Wu
Journal:  Phys Life Rev       Date:  2015-02-20       Impact factor: 11.025

2.  Dynamic semiparametric Bayesian models for genetic mapping of complex trait with irregular longitudinal data.

Authors:  Kiranmoy Das; Jiahan Li; Guifang Fu; Zhong Wang; Runze Li; Rongling Wu
Journal:  Stat Med       Date:  2012-08-17       Impact factor: 2.373

3.  Systems mapping: how to improve the genetic mapping of complex traits through design principles of biological systems.

Authors:  Rongling Wu; Jiguo Cao; Zhongwen Huang; Zhong Wang; Junyi Gai; Eduardo Vallejos
Journal:  BMC Syst Biol       Date:  2011-05-27

4.  Multiallelic epistatic model for an out-bred cross and mapping algorithm of interactive quantitative trait loci.

Authors:  Chunfa Tong; Bo Zhang; Zhong Wang; Meng Xu; Xiaoming Pang; Jingna Si; Minren Huang; Rongling Wu
Journal:  BMC Plant Biol       Date:  2011-10-31       Impact factor: 4.215

  4 in total

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