| Literature DB >> 20160841 |
Fei Zou1, Lei Nie, Fred A Wright, Pranab K Sen.
Abstract
In quantitative-trait linkage studies using experimental crosses, the conventional normal location-shift model or other parameterizations may be unnecessarily restrictive. We generalize the mapping problem to a genuine nonparametric setup and provide a robust estimation procedure for the situation where the underlying phenotype distributions are completely unspecified. Classical Wilcoxon-Mann-Whitney statistics are employed for point and interval estimation of QTL positions and effects.Entities:
Year: 2009 PMID: 20160841 PMCID: PMC2632598 DOI: 10.1016/j.jspi.2008.06.009
Source DB: PubMed Journal: J Stat Plan Inference ISSN: 0378-3758 Impact factor: 1.111