Literature DB >> 201599

beta-Lactamase and beta-lactam antibiotics resistance in acinetobacter anitratum (syn: A. calcoaceticus).

T Morohoshi, T Saito.   

Abstract

The cephalosporin beta-lactamase (cephalosporinase) produced by Acinetobacter was studied. The enzyme was partially purified by means of column chromatography and its properties were investigated. The enzyme was induced by benzylpenicillin, 6-aminopenicillanic acid and cephaloridine. Its molecular weight is 30,000 its optimal temperature 40C, and its optimal pH 7.25 similar to 7.50. Substrate specificity studies using various cephalosporins and penicillins, showed that the enzyme functioned as a cephalosporinase rather than penicillinase.

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Year:  1977        PMID： 201599     DOI： 10.7164/antibiotics.30.969

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  13 in total

Review 1.  Classification of beta-lactamases: groups 1, 2a, 2b, and 2b'.

Authors:  K Bush
Journal:  Antimicrob Agents Chemother       Date:  1989-03       Impact factor: 5.191

2.  Dissemination of amikacin resistance gene aphA6 in Acinetobacter spp.

Authors:  T Lambert; G Gerbaud; P Bouvet; J F Vieu; P Courvalin
Journal:  Antimicrob Agents Chemother       Date:  1990-06       Impact factor: 5.191

Review 3.  Acinetobacter spp. as nosocomial pathogens: microbiological, clinical, and epidemiological features.

Authors:  E Bergogne-Bérézin; K J Towner
Journal:  Clin Microbiol Rev       Date:  1996-04       Impact factor: 26.132

Review 4.  A functional classification scheme for beta-lactamases and its correlation with molecular structure.

Authors:  K Bush; G A Jacoby; A A Medeiros
Journal:  Antimicrob Agents Chemother       Date:  1995-06       Impact factor: 5.191

5.  Antimicrobial susceptibility of Acinetobacter species.

Authors:  H Seifert; R Baginski; A Schulze; G Pulverer
Journal:  Antimicrob Agents Chemother       Date:  1993-04       Impact factor: 5.191

6.  Characterization of the chromosomal cephalosporinases produced by Acinetobacter lwoffii and Acinetobacter baumannii clinical isolates.

Authors:  M Perilli; A Felici; A Oratore; G Cornaglia; G Bonfiglio; G M Rossolini; G Amicosante
Journal:  Antimicrob Agents Chemother       Date:  1996-03       Impact factor: 5.191

7.  In vitro antimicrobial production of beta-lactamases, aminoglycoside-modifying enzymes, and chloramphenicol acetyltransferase by and susceptibility of clinical isolates of Acinetobacter baumannii.

Authors:  J Vila; A Marcos; F Marco; S Abdalla; Y Vergara; R Reig; R Gomez-Lus; T Jimenez de Anta
Journal:  Antimicrob Agents Chemother       Date:  1993-01       Impact factor: 5.191

8.  Aminoglycoside-modifying enzymes among clinical isolates of Acinetobacter calcoaceticus subsp. anitratus (Herellea vaginicola): explanation for high-level aminoglycoside resistance.

Authors:  B E Murray; R C Moellering
Journal:  Antimicrob Agents Chemother       Date:  1979-02       Impact factor: 5.191

9.  Transferable amikacin resistance in Acinetobacter spp. due to a new type of 3'-aminoglycoside phosphotransferase.

Authors:  T Lambert; G Gerbaud; P Courvalin
Journal:  Antimicrob Agents Chemother       Date:  1988-01       Impact factor: 5.191

10.  Studies on New Delhi Metallo-Beta-Lactamse-1 producing Acinetobacter baumannii isolated from donor swab in a tertiary eye care centre, India and structural analysis of its antibiotic binding interactions.

Authors:  Murali Sowmiya; Vetrivel Umashankar; Sivashanmugan Muthukumaran; Hajib Naraharirao Madhavan; Jambulingam Malathi
Journal:  Bioinformation       Date:  2012-05-31
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