Literature DB >> 20159605

Obesity, inflammatory signaling, and hepatocellular carcinoma-an enlarging link.

Sara Toffanin1, Scott L Friedman, Josep M Llovet.   

Abstract

There is growing evidence that obesity increases the risk of hepatocellular carcinoma (HCC). In a recent issue of Cell, Park et al. show that IL-6 and TNF signaling through activation of STAT3 are critical for obesity-promoted HCC development, underscoring the important role of inflammatory pathways in hepatocarcinogenesis. 2010 Elsevier Inc. All rights reserved.

Entities:  

Year:  2010        PMID： 20159605     DOI： 10.1016/j.ccr.2010.01.018

Source DB:  PubMed          Journal:  Cancer Cell        ISSN： 1535-6108            Impact factor:   31.743


  20 in total

1.  CellMinerHCC: a microarray-based expression database for hepatocellular carcinoma cell lines.

Authors:  Frank Staib; Markus Krupp; Thorsten Maass; Timo Itzel; Arndt Weinmann; Ju-Seog Lee; Bertil Schmidt; Martina Müller; Snorri S Thorgeirsson; Peter R Galle; Andreas Teufel
Journal:  Liver Int       Date:  2013-09-09       Impact factor: 5.828

Review 2.  STAT3 in hepatocellular carcinoma: new perspectives.

Authors:  Jasmin Svinka; Wolfgang Mikulits; Robert Eferl
Journal:  Hepat Oncol       Date:  2013-12-20

Review 3.  Repositioning metformin in cancer: genetics, drug targets, and new ways of delivery.

Authors:  Mihaela Aldea; Lucian Craciun; Ciprian Tomuleasa; Ioana Berindan-Neagoe; Gabriel Kacso; Ioan Stefan Florian; Carmen Crivii
Journal:  Tumour Biol       Date:  2014-02-07

4.  Blocking the CCL2-CCR2 Axis Using CCL2-Neutralizing Antibody Is an Effective Therapy for Hepatocellular Cancer in a Mouse Model.

Authors:  Kun-Yu Teng; Jianfeng Han; Xiaoli Zhang; Shu-Hao Hsu; Shun He; Nissar A Wani; Juan M Barajas; Linda A Snyder; Wendy L Frankel; Michael A Caligiuri; Samson T Jacob; Jianhua Yu; Kalpana Ghoshal
Journal:  Mol Cancer Ther       Date:  2016-12-15       Impact factor: 6.261

Review 5.  Obesity, inflammation, and liver cancer.

Authors:  Beicheng Sun; Michael Karin
Journal:  J Hepatol       Date:  2011-11-25       Impact factor: 25.083

6.  Inhibition of autocrine IGF-II on effect of human HepG2 cell proliferation and angiogenesis factor expression.

Authors:  Ninghua Yao; Dengfu Yao; Li Wang; Zhizhen Dong; Wei Wu; Liwei Qiu; Xiaodi Yan; Dandan Yu; Jie Chen; Wenli Sai; Haijian Zhang; Junlin Yang
Journal:  Tumour Biol       Date:  2012-06-10

7.  ER stress cooperates with hypernutrition to trigger TNF-dependent spontaneous HCC development.

Authors:  Hayato Nakagawa; Atsushi Umemura; Koji Taniguchi; Joan Font-Burgada; Debanjan Dhar; Hisanobu Ogata; Zhenyu Zhong; Mark A Valasek; Ekihiro Seki; Juan Hidalgo; Kazuhiko Koike; Randal J Kaufman; Michael Karin
Journal:  Cancer Cell       Date:  2014-08-14       Impact factor: 31.743

8.  p62/SQSTM1 by Binding to Vitamin D Receptor Inhibits Hepatic Stellate Cell Activity, Fibrosis, and Liver Cancer.

Authors:  Angeles Duran; Eloy D Hernandez; Miguel Reina-Campos; Elias A Castilla; Shankar Subramaniam; Sindhu Raghunandan; Lewis R Roberts; Tatiana Kisseleva; Michael Karin; Maria T Diaz-Meco; Jorge Moscat
Journal:  Cancer Cell       Date:  2016-10-10       Impact factor: 31.743

Review 9.  Inflammation- and stress-related signaling pathways in hepatocarcinogenesis.

Authors:  Hayato Nakagawa; Shin Maeda
Journal:  World J Gastroenterol       Date:  2012-08-21       Impact factor: 5.742

10.  Central Leptin and Tumor Necrosis Factor-α (TNFα) in Diurnal Control of Blood Pressure and Hypertension.

Authors:  Cheng Han; Wenhe Wu; Albert Ale; Min Soo Kim; Dongsheng Cai
Journal:  J Biol Chem       Date:  2016-05-13       Impact factor: 5.157
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