OBJECTIVE: To examine associations between cognitive and affective impairments and rehabilitation participation during stroke rehabilitation. DESIGN: Secondary analyses of stroke patients who received acetylcholinesterase inhibitors during inpatient rehabilitation. SETTING: University-affiliated inpatient rehabilitation facilities. PARTICIPANTS: Patients (N=44) admitted to inpatient stroke rehabilitation with impairment in attention, memory, or executive functions. INTERVENTIONS: Secondary analysis of patients receiving inpatient stroke rehabilitation care plus random assignment to one of two acetylcholinesterase inhibitors or no drug at rehabilitation admission. MAIN OUTCOME MEASURES: Correlations between measures of cognitive (Digit Span, Hopkins Verbal Learning Test, Executive Interview) and affective impairments (Hamilton Rating Scale for Depression, Apathy Evaluation Scale) and participation (Pittsburgh Rehabilitation and Participation Scale) were examined. Significant correlates of participation were examined in a linear multiple regression model. RESULTS:Executive functions and depressive symptoms were significant correlates of participation. After controlling for baseline disability, executive functions predicted participation, but depressive symptoms did not (F(4,32)=9.35; R(2)=.54, P<.001). CONCLUSIONS: These findings are an important first step toward understanding potentially modifiable clinical factors that contribute to rehabilitation participation and overall functional status after rehabilitation. A better understanding of cognitive impairment and rehabilitation participation may be used to develop strategies for improving functional outcomes after stroke. Copyright 2010 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.
RCT Entities:
OBJECTIVE: To examine associations between cognitive and affective impairments and rehabilitation participation during stroke rehabilitation. DESIGN: Secondary analyses of strokepatients who received acetylcholinesterase inhibitors during inpatient rehabilitation. SETTING: University-affiliated inpatient rehabilitation facilities. PARTICIPANTS: Patients (N=44) admitted to inpatient stroke rehabilitation with impairment in attention, memory, or executive functions. INTERVENTIONS: Secondary analysis of patients receiving inpatient stroke rehabilitation care plus random assignment to one of two acetylcholinesterase inhibitors or no drug at rehabilitation admission. MAIN OUTCOME MEASURES: Correlations between measures of cognitive (Digit Span, Hopkins Verbal Learning Test, Executive Interview) and affective impairments (Hamilton Rating Scale for Depression, Apathy Evaluation Scale) and participation (Pittsburgh Rehabilitation and Participation Scale) were examined. Significant correlates of participation were examined in a linear multiple regression model. RESULTS: Executive functions and depressive symptoms were significant correlates of participation. After controlling for baseline disability, executive functions predicted participation, but depressive symptoms did not (F(4,32)=9.35; R(2)=.54, P<.001). CONCLUSIONS: These findings are an important first step toward understanding potentially modifiable clinical factors that contribute to rehabilitation participation and overall functional status after rehabilitation. A better understanding of cognitive impairment and rehabilitation participation may be used to develop strategies for improving functional outcomes after stroke. Copyright 2010 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.
Authors: Helen H Dorra; Eric J Lenze; Yookyung Kim; Benoit H Mulsant; Michael C Munin; Mary Amanda Dew; Charles F Reynolds Journal: Int J Psychiatry Med Date: 2002 Impact factor: 1.210
Authors: Eric J Lenze; Michael C Munin; Tanya Quear; Mary Amanda Dew; Joan C Rogers; Amy E Begley; Charles F Reynolds Journal: Arch Phys Med Rehabil Date: 2004-10 Impact factor: 3.966
Authors: Eric J Lenze; Michael C Munin; Mary Amanda Dew; Joan C Rogers; Karen Seligman; Benoit H Mulsant; Charles F Reynolds Journal: Int J Geriatr Psychiatry Date: 2004-05 Impact factor: 3.485
Authors: Eric J Lenze; Michael C Munin; Tanya Quear; Mary Amanda Dew; Joan C Rogers; Amy E Begley; Charles F Reynolds Journal: Arch Phys Med Rehabil Date: 2004-03 Impact factor: 3.966
Authors: Elizabeth R Skidmore; Deirdre R Dawson; Ellen M Whyte; Meryl A Butters; Mary Amanda Dew; Emily S Grattan; James T Becker; Margo B Holm Journal: Clin Rehabil Date: 2013-10-10 Impact factor: 3.477
Authors: Judith E Goldstein; Robert W Massof; James T Deremeik; Sonya Braudway; Mary Lou Jackson; K Bradley Kehler; Susan A Primo; Janet S Sunness Journal: Arch Ophthalmol Date: 2012-08
Authors: James T Becker; Mary Amanda Dew; Howard J Aizenstein; Oscar L Lopez; Lisa Morrow; Judith Saxton; Lluís Tárraga Journal: Disabil Rehabil Date: 2012-03-30 Impact factor: 3.033