Literature DB >> 20155793

Propensity scored analysis of outcomes after ruptured abdominal aortic aneurysm.

P J E Holt1, A Karthikesalingam, J D Poloniecki, R J Hinchliffe, I M Loftus, M M Thompson.   

Abstract

BACKGROUND: This study examined the population outcome of ruptured abdominal aortic aneurysm (rAAA) in England, the role of endovascular repair (EVAR), and the relationship between outcome and hospital workload.
METHODS: Data were retrieved from Hospital Episode Statistics between 1 April 2003 and 31 March 2008. Propensity scoring was used to compare the outcomes of stratified patients undergoing EVAR and open repair. The relationship between workload and outcome was determined.
RESULTS: Some 3725 urgent and 4414 rAAA repairs were included. Mortality rates were 21.3 per cent for urgent repair and 46.3 per cent for rAAA repair. EVAR was employed for 16.3 and 7.6 per cent of urgent and rAAA repairs respectively. EVAR was associated with significantly reduced mortality for urgent repair (odds ratio (OR) 0.531, 95 per cent confidence interval 0.415 to 0.680; P < 0.001) and rAAA repair (OR 0.527, 0.416 to 0.668; P < 0.001). A propensity scored analysis confirmed the benefit of EVAR for rAAA repair (P < 0.001). Repair of rAAA at hospitals with a higher elective aneurysm workload was associated with lower mortality rates irrespective of the mode of treatment (P < 0.001). Higher-volume hospitals were more likely to operate on rAAA (P = 0.033).
CONCLUSION: EVAR offered a survival advantage over open repair for non-elective aneurysm procedures. Services for the treatment of rAAA should incorporate access to EVAR and would benefit from being based in units with a high elective caseload. Copyright (c) 2010 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.

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Year:  2010        PMID: 20155793     DOI: 10.1002/bjs.6911

Source DB:  PubMed          Journal:  Br J Surg        ISSN: 0007-1323            Impact factor:   6.939


  14 in total

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3.  External Validation of Risk Stratification Models Predicting the Immediate Mortality After Open Repair of Ruptured AAA.

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4.  Mortality rates and risk factors for emergent open repair of abdominal aortic aneurysms in the endovascular era.

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Journal:  Updates Surg       Date:  2017-09-14

5.  Surgeon elective abdominal aortic aneurysm repair volume and outcomes of ruptured abdominal aortic aneurysm repair: a 12-year nationwide study.

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6.  Comparative effectiveness of endovascular versus open repair of ruptured abdominal aortic aneurysm in the Medicare population.

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7.  Transfer of patients with ruptured abdominal aortic aneurysm from general hospitals to specialist vascular centres: results of a Delphi consensus study.

Authors:  Robert J Hinchliffe; Tamsin Ribbons; Pinar Ulug; Janet T Powell
Journal:  Emerg Med J       Date:  2012-07-03       Impact factor: 2.740

8.  Towards national surgical surveillance in the UK--a pilot study.

Authors:  Riaz Agha
Journal:  PLoS One       Date:  2012-12-11       Impact factor: 3.240

Review 9.  Emergent endovascular vs. open surgery repair for ruptured abdominal aortic aneurysms: a meta-analysis.

Authors:  Chuan Qin; Lin Chen; Ying-bin Xiao
Journal:  PLoS One       Date:  2014-01-31       Impact factor: 3.240

Review 10.  Endovascular vs. Open Repair for Ruptured Abdominal Aortic Aneurysm.

Authors:  Nikolaos Patelis; Demetrios Moris; Georgios Karaolanis; Sotiris Georgopoulos
Journal:  Med Sci Monit Basic Res       Date:  2016-04-19
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