Literature DB >> 28913787

Mortality rates and risk factors for emergent open repair of abdominal aortic aneurysms in the endovascular era.

Felice Pecoraro1,2, Steffen Gloekler3, Caecilia E Mader4, Malgorzata Roos5, Lyubov Chaykovska6, Frank J Veith7, Neal S Cayne7, Nicola Mangialardi8, Thomas Neff9, Mario Lachat6.   

Abstract

The background of this paper is to report the mortality at 30 and 90 days and at mean follow-up after open abdominal aortic aneurysms (AAA) emergent repair and to identify predictive risk factors for 30- and 90-day mortality. Between 1997 and 2002, 104 patients underwent emergent AAA open surgery. Symptomatic and ruptured AAAs were observed, respectively, in 21 and 79% of cases. Mean patient age was 70 (SD 9.2) years. Mean aneurysm maximal diameter was 7.4 (SD 1.6) cm. Primary endpoints were 30- and 90-day mortality. Significant mortality-related risk factor identification was the secondary endpoint. Open repair trend and its related perioperative mortality with a per-year analysis and a correlation subanalysis to identify predictive mortality factor were performed. Mean follow-up time was 23 (SD 23) months. Overall, 30-day mortality was 30%. Significant mortality-related risk factors were the use of computed tomography (CT) as a preoperative diagnostic tool, AAA rupture, preoperative shock, intraoperative cardiopulmonary resuscitation (CPR), use of aortic balloon occlusion, intraoperative massive blood transfusion (MBT), and development of abdominal compartment syndrome (ACS). Previous abdominal surgery was identified as a protective risk factor. The mortality rate at 90 days was 44%. Significant mortality-related risk factors were AAA rupture, aortocaval fistula, peripheral artery disease (PAD), preoperative shock, CPR, MBT, and ACS. The mortality rate at follow-up was 45%. Correlation analysis showed that MBT, shock, and ACS are the most relevant predictive mortality factor at 30 and 90 days. During the transition period from open to endovascular repair, open repair mortality outcomes remained comparable with other contemporary data despite a selection bias for higher risk patients. MBT, shock, and ACS are the most pronounced predictive mortality risk factors.

Entities:  

Keywords:  Abdominal aortic aneurysm; Endovascular aneurysm repair; Mortality; Open repair; Ruptured; Symptomatic

Mesh:

Year:  2017        PMID: 28913787     DOI: 10.1007/s13304-017-0488-y

Source DB:  PubMed          Journal:  Updates Surg        ISSN: 2038-131X


  30 in total

Review 1.  A meta-analysis of 50 years of ruptured abdominal aortic aneurysm repair.

Authors:  M J Bown; A J Sutton; P R F Bell; R D Sayers
Journal:  Br J Surg       Date:  2002-06       Impact factor: 6.939

2.  A meta-analysis of randomized and risk-adjusted observational studies of endovascular versus open repair for ruptured abdominal aortic aneurysm.

Authors:  Hisato Takagi; Takuya Umemoto
Journal:  Vasc Endovascular Surg       Date:  2011-11       Impact factor: 1.089

Review 3.  Current role for endovascular treatment of ruptured abdominal aortic aneurysms.

Authors:  Frank J Veith; Neal S Cayne; Todd L Berland; Dieter Mayer; Mario Lachat
Journal:  Semin Vasc Surg       Date:  2012-09       Impact factor: 1.000

Review 4.  Literature review of surgical management of abdominal aortic aneurysm.

Authors:  A Hallin; D Bergqvist; L Holmberg
Journal:  Eur J Vasc Endovasc Surg       Date:  2001-09       Impact factor: 7.069

Review 5.  The pathophysiology of skeletal muscle ischemia and the reperfusion syndrome: a review.

Authors:  F William Blaisdell
Journal:  Cardiovasc Surg       Date:  2002-12

6.  Ruptured abdominal aortic aneurysms: analysis of factors influencing surgical results in 184 patients.

Authors:  S Sasaki; M Sakuma; M Samejima; T Kunihara; N Shiiya; T Murashita; Y Matsui; K Yasuda
Journal:  J Cardiovasc Surg (Torino)       Date:  1999-06       Impact factor: 1.888

7.  Influence of coronary artery disease on operative mortality and long-term survival after abdominal aortic aneurysm repair.

Authors:  Yasuyuki Sasaki; Fumitaka Isobe; Seiji Kinugasa; Keiji Iwata; Tadahiro Murakami; Motoko Saito; Manabu Motoki
Journal:  Surg Today       Date:  2004       Impact factor: 2.549

8.  Endovascular repair with bifurcated stent-grafts under local anaesthesia to improve outcome of ruptured aortoiliac aneurysms.

Authors:  M L Lachat; Th Pfammatter; H J Witzke; D Bettex; A Künzli; U Wolfensberger; M I Turina
Journal:  Eur J Vasc Endovasc Surg       Date:  2002-06       Impact factor: 7.069

Review 9.  Systematic review: repair of unruptured abdominal aortic aneurysm.

Authors:  Frank A Lederle; Robert L Kane; Roderick MacDonald; Timothy J Wilt
Journal:  Ann Intern Med       Date:  2007-05-15       Impact factor: 25.391

10.  Statistical and data reporting guidelines for the European Journal of Cardio-Thoracic Surgery and the Interactive CardioVascular and Thoracic Surgery.

Authors:  Graeme L Hickey; Joel Dunning; Burkhardt Seifert; Gottfried Sodeck; Matthew J Carr; Hans Ulrich Burger; Friedhelm Beyersdorf
Journal:  Eur J Cardiothorac Surg       Date:  2015-05-12       Impact factor: 4.191

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  3 in total

1.  Association of Functional, Cognitive, and Psychological Measures With 1-Year Mortality in Patients Undergoing Major Surgery.

Authors:  Victoria L Tang; Bocheng Jing; John Boscardin; Sarah Ngo; Molly Silvestrini; Emily Finlayson; Kenneth E Covinsky
Journal:  JAMA Surg       Date:  2020-05-01       Impact factor: 14.766

2.  Contemporary mortality after emergent open repair of complex abdominal aortic aneurysms.

Authors:  Christopher A Latz; Laura Boitano; Samuel Schwartz; Nicholas Swerdlow; Kirsten Dansey; Rens R B Varkevisser; Virendra Patel; Marc Schermerhorn
Journal:  J Vasc Surg       Date:  2020-04-29       Impact factor: 4.268

3.  Routine open abdomen treatment compared with on-demand open abdomen or direct closure following open repair of ruptured abdominal aortic aneurysms: A propensity score-matched study.

Authors:  Kristian Smidfelt; Joakim Nordanstig; Urban Wingren; Göran Bergström; Marcus Langenskiöld
Journal:  SAGE Open Med       Date:  2019-02-25
  3 in total

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