Literature DB >> 20148205

"Click" labeling strategy for M(CO)(3) (M = Re, (99m)Tc) prostate cancer targeted flutamide agents.

Adam L Moore1, Dejan-Kresimir Bucar, Leonard R Macgillivray, Paul D Benny.   

Abstract

Two distinct "click" chemistry labeling approaches were investigated with dipyridylamine alkyne derivatives and M(CO)(3)(+) (M = Re, (99m)Tc). The triazole ring was found uncoordinated and was incorporated into the preparation of a crossover androgen receptor targeting inhibitor for prostate cancer.

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Year:  2010        PMID： 20148205     DOI： 10.1039/b921413e

Source DB:  PubMed          Journal:  Dalton Trans        ISSN： 1477-9226            Impact factor:   4.390


  6 in total

1.  Inorganic chemistry in nuclear imaging and radiotherapy: current and future directions.

Authors:  Valerie Carroll; Dustin W Demoin; Timothy J Hoffman; Silvia S Jurisson
Journal:  Radiochim Acta       Date:  2012-08       Impact factor: 1.440

2.  Rhenium and technetium bi- and tricarbonyl complexes in a new strategy for biomolecule incorporation using click chemistry.

Authors:  Thomas R Hayes; Benjamin B Kasten; Charles L Barnes; Paul D Benny
Journal:  Dalton Trans       Date:  2014-04-07       Impact factor: 4.390

3.  Underscoring the influence of inorganic chemistry on nuclear imaging with radiometals.

Authors:  Brian M Zeglis; Jacob L Houghton; Michael J Evans; Nerissa Viola-Villegas; Jason S Lewis
Journal:  Inorg Chem       Date:  2013-12-06       Impact factor: 5.165

4.  Isothiocyanate-Functionalized Bifunctional Chelates and fac-[M(I)(CO)3](+) (M = Re, (99m)Tc) Complexes for Targeting uPAR in Prostate Cancer.

Authors:  Benjamin B Kasten; Xiaowei Ma; Kai Cheng; Lihong Bu; Winston S Slocumb; Thomas R Hayes; Steven Trabue; Zhen Cheng; Paul D Benny
Journal:  Bioconjug Chem       Date:  2015-12-30       Impact factor: 4.774

5.  Cu-free 1,3-dipolar cycloaddition click reactions to form isoxazole linkers in chelating ligands for fac-[M(I)(CO)3]+ centers (M = Re, 99mTc).

Authors:  Shalina C Bottorff; Benjamin B Kasten; Jelena Stojakovic; Adam L Moore; Leonard R MacGillivray; Paul D Benny
Journal:  Inorg Chem       Date:  2014-01-31       Impact factor: 5.165

6.  Clickable, hydrophilic ligand for fac-[M(I)(CO)3](+) (M = Re/(99m)Tc) applied in an S-functionalized α-MSH peptide.

Authors:  Benjamin B Kasten; Xiaowei Ma; Hongguang Liu; Thomas R Hayes; Charles L Barnes; Shibo Qi; Kai Cheng; Shalina C Bottorff; Winston S Slocumb; Jing Wang; Zhen Cheng; Paul D Benny
Journal:  Bioconjug Chem       Date:  2014-02-25       Impact factor: 4.774
  6 in total

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