Literature DB >> 2014169

Polymorphisms generated by arbitrarily primed PCR in the mouse: application to strain identification and genetic mapping.

J Welsh1, C Petersen, M McClelland.   

Abstract

Polymorphisms in genomic fingerprints generated by arbitrarily primed PCR (AP-PCR) can distinguish between strains of almost any organism. We applied the technique to the mouse (Mus musculus). The characteristic differences in the AP-PCR genomic fingerprints between strains will be of value in strain identification and verification. Using one primer, we genetically mapped four polymorphisms in a set of C57BL/6J x DBA/2J recombinant inbreds. One of these polymorphisms is a length variant. The method will allow rapid genetic mapping of DNA polymorphisms without Southern blotting.

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Year:  1991        PMID： 2014169      PMCID： PMC333594          DOI： 10.1093/nar/19.2.303

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  14 in total

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Journal:  Trends Genet       Date:  1988-01       Impact factor: 11.639

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5.  A hypervariable microsatellite revealed by in vitro amplification of a dinucleotide repeat within the cardiac muscle actin gene.

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Journal:  Nucleic Acids Res       Date:  1983-04-11       Impact factor: 16.971

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  69 in total

1.  Randomly amplified polymorphic DNA-polymerase chain reaction analysis of two different populations of cultured Korean catfish Silurus asotus.

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Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

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Journal:  Appl Environ Microbiol       Date:  1992-05       Impact factor: 4.792

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