OBJECTIVES: Several adverse pregnancy outcomes were reported among female laboratory workers in a North American aluminum smelter. To determine whether these outcomes were associated with any occupational exposure at the plant, a cross-sectional survey was undertaken. METHODS: Rates of miscarriage, premature singleton birth, and major congenital anomaly occurring during employment were compared with a reference group comprised of all pregnancies that occurred before employment. RESULTS: Among female workers, the excess of congenital anomalies among female laboratory workers that defined the initial cluster was observed, but no specific pattern was found. CONCLUSIONS: On the basis of these analyses, the increase in congenital anomalies could not be attributed to occupational exposures at the smelter nor could potential exposure likely explain the diverse anomalies described.
OBJECTIVES: Several adverse pregnancy outcomes were reported among female laboratory workers in a North American aluminum smelter. To determine whether these outcomes were associated with any occupational exposure at the plant, a cross-sectional survey was undertaken. METHODS: Rates of miscarriage, premature singleton birth, and major congenital anomaly occurring during employment were compared with a reference group comprised of all pregnancies that occurred before employment. RESULTS: Among female workers, the excess of congenital anomalies among female laboratory workers that defined the initial cluster was observed, but no specific pattern was found. CONCLUSIONS: On the basis of these analyses, the increase in congenital anomalies could not be attributed to occupational exposures at the smelter nor could potential exposure likely explain the diverse anomalies described.
Authors: Frederica P Perera; Virginia Rauh; Wei-Yann Tsai; Patrick Kinney; David Camann; Dana Barr; Tom Bernert; Robin Garfinkel; Yi-Hsuan Tu; Diurka Diaz; Jessica Dietrich; Robin M Whyatt Journal: Environ Health Perspect Date: 2003-02 Impact factor: 9.031
Authors: Holly Elser; Andreas M Neophytou; Erika Tribett; Deron Galusha; Sepideh Modrek; Elizabeth M Noth; Valerie Meausoone; Ellen A Eisen; Linda F Cantley; Mark R Cullen Journal: Int J Epidemiol Date: 2019-10-01 Impact factor: 7.196